Without a Prescription

At the start of Zyprexa therapy, the drug can cause extreme low blood pressure, increased heart rate, dizziness, and, in rare cases, a tendency to faint when first standing up.
It is thought to work by opposing the action of serotonin and dopamine, two of the brain's major chemical messengers.
The drug is available as Zyprexa tablets and Zyprexa Zydis, which dissolves rapidly with or without liquid.
These problems are more likely if you are dehydrated, have heart disease, or take blood pressure medicine.
To avoid such problems, your doctor may start with a low dose of Zyprexa and increase the dosage gradually.
Zyprexa helps manage symptoms of schizophrenia, the manic phase of manic-depression, and other psychotic disorders.

Side Effects

Zyprexa side effects that you should report to your health care professional or doctor as soon as possible:

More common side effects may include:
- Weight gain;
- Weakness;
- Tremor;
- Tension;
- Restlessness;
- Rapid heartbeat;
- Pain in arms and legs;
- Nervousness;
- Nausea;
- Muscle rigidity;
- Movement disorders;
- Joint pain;
- Insomnia;
- Inflammation of the nasal passages and throat;
- Indigestion;
- Increased cough;
- Increased appetite;
- Hostility;
- High blood pressure;
- Headache;
- Fever;
- Feeling of well-being;
- Eye problems;
- Extreme low blood pressure;
- Dry mouth;
- Drowsiness;
- Dizziness;
- Dehydration;
- Cough;
- Constipation;
- Chest pain;
- Blurred vision;
- Blood in urine;
- Behavior problems;
- Back pain;
- Anxiety;
- Agitation;
- Accidental injury;
- Abnormal gait;
- Abdominal pain;

Less common side effects may include:
- Vomiting;
- Vaginal infection;
- Urinary problems;
- Twitching;
- Thirst;
- Swelling of arms and legs;
- Sweating;
- Suicide attempts;
- Sore throat;
- Sleepiness;
- Nasal stuffiness;
- Menstrual irregularities;
- Low blood pressure;
- Joint stiffness;
- Involuntary movement;
- Intentional injury;
- Increased salivation;
- Eye infection;
- Emotional instability;
- Difficulty breathing;
- Diabetes;
- Dental pain;
- Decreased sex drive;
- Abnormal dreams;

Rare side effects may include:
- Yeast infection;
- Swollen gums;
- Swelling of face;
- Sudden death;
- Stroke;
- Stomach upset;
- Sensitivity to light;
- Ringing in the ears;
- Rheumatoid arthritis;
- Rectal bleeding;
- Rash;
- Pallor;
- Osteoporosis;
- Neck rigidity;
- Neck pain;
- Mouth sores;
- Migraine;
- Inability to control bowel movements;
- Heart attack;
- Hangover feeling;
- Hair loss;
- Gas;
- Fever;
- Enlarged abdomen;
- Ear pain;
- Dry skin;
- Dry eyes;
- Difficulty swallowing;
- Congestive heart failure;
- Chills;
- Change in taste sensation;
- Burping;
- Breast pain;
- Breast growth in males;
- Bone pain;
- Blood clots;
- Bleeding;
- Black bowel movements;
- Abnormal ejaculation;


Zyprexa is contraindicated if you have any of the following conditions:
- If you have a child with phenylketonuria (the inability to process phenylalanine, a condition that quickly leads to mental retardation);
- If Zyprexa gives you an allergic reaction;

if you have any of the following conditions:
- Trouble swallowing;
- Seizures;
- Parkinson's disease;
- A history of heart attack;
- Narrow angle glaucoma (high pressure in the eye);
- Liver disease;
- Intestinal blockage;
- Heart irregularities;
- Heart failure;
- Heart disease;
- An enlarged prostate;
- Alzheimer's disease;


Do not take Zyprexa with any of the following drugs:
- Rifampin (rifadin, rimactane);
- Omeprazole (prilosec);
- Levodopa (larodopa);
- Fluvoxamine (luvox);
- Drugs that boost the effect of dopamine, such as the parkinson's medications mirapex, parlodel, permax, and requip;
- Diazepam (valium);
- Carbamazepine (tegretol);
- Blood pressure medications;



Manic Episodes in Manic-Depression

The drug is typically taken for no more than 3 or 4 weeks at a time.
The usual starting dose is 10 to 15 milligrams once a day.


The usual starting dose is 5 to 10 milligrams once a day.
After that, the dosage will be increased no more than once a week, 5 milligrams at a time, up to a maximum of 20 milligrams a day.
If you start at the lower dose, after a few days the doctor will increase it to 10.
Those most likely to start at 5 milligrams are the debilitated, people prone to low blood pressure, and nonsmoking women over 65 (because they tend to have a slow metabolism).


Symptoms of Zyprexa overdose may include:
- Stupor;
- Slurred or disrupted speech;
- Rapid or irregular heartbeat;
- Drowsiness;
- Agitation;

Overdoses of Zyprexa have also:
- Cardiac arrest;
- Changes in blood pressure;
- Coma;
- Convulsions;
- Excessive perspiration;
- Fever;
- Led to breathing difficulties;
- Muscle rigidity;
Without Prescription (2017)