Zonisamide

 
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Without a Prescription

Zonisamide controls the convulsions (fits) suffered by people with epilepsy by reducing the activity of the central nervous system.
Zonisamide is prescribed for use as adjunctive treatment of partial seizures in adults with epilepsy.
Zonisamide is prescribed with other medications to prevent and control seizures (epilepsy).
Zonisamide is usually given with other medicines for epilepsy.

Contraindications

Zonisamide is contraindicated if you have any of the following conditions:
- If you are pregnant, trying for a baby or breast-feeding;
- If you have ever had an allergic reaction to a group of drugs called sulphonamides;
- If you have ever had kidney stones;
- If you have kidney or liver problems;
- if you are allergic to Zonisamide;
- if you have a special diet (ketogenic diet);
- if you have any other allergies;
- if you have kidney disease (kidney stones);
- if you have liver disease;
- if you have long-term diarrhea;
- if you have lung/breathing problems;
- if you have mental/mood problems (depression, psychosis);
- if you have metabolic imbalance (metabolic acidosis);

Interactions

Do not take Zonisamide with any of the following drugs:
- Alcohol;
- Alprazolam;
- And narcotic pain relievers (codeine);
- Antihistamines;
- Carbamazepine;
- Carbonic anhydrase inhibitors (acetazolamide);
- Cetirizine;
- Diazepam;
- Diphenhydramine;
- Drugs for sleep or anxiety;
- Muscle relaxants;
- Phenobarbital;
- Phenytoin;
- Primidone;
- Rifamycins (rifabutin);
- St John's wort;
- Zolpidem;

Side Effects

Zonisamide side effects that you should report to your health care professional or doctor as soon as possible:
- Anxiety;
- Being sick;
- Bipolar disorder;
- Bruising;
- Change in the amount of urine;
- Confusion;
- Constipation;
- Dark/bloody urine;
- Decreased sweating;
- Depression;
- Diarrhea;
- Diarrhoea;
- Dizziness;
- Double vision;
- Drowsiness;
- Easy bruising/bleeding;
- Fainting;
- Fast/irregular heartbeat;
- Feeling depressed;
- Feeling irritable;
- Fever;
- Heat stroke;
- Itching/swelling (especially of the face/tongue/throat);
- Itching;
- Kidney stone disease;
- Kidney stones;
- Lack of appetite;
- Lack of coordination;
- Loss of appetite;
- Nausea;
- Numb/tingling skin;
- Other mental/mood problems;
- Pain;
- Persistent sore throat);
- 'pins and needles';
- Poor concentration;
- Problems sleeping;
- Problems with speech;
- Problems with vision;
- Rapid breathing;
- Rash;
- Seeing or hearing things that are not real;
- Seizure;
- Severe dizziness;
- Severe stomach/abdominal pain;
- Shakiness;
- Signs of infection (such as fever;
- Slowed thinking;
- Speech problems;
- Suicidal thoughts/attempts;
- Tiredness;
- Trouble breathing;
- Trouble sleeping;
- Unusual eye movements (nystagmus);
- Unusual tiredness;
- Visual changes;
- Weight loss;
- Yellowing eyes/skin;

Overdose

Reported Zonisamide overdose symptoms are:
- Diminished breathing;
- Loss of consciousness;
- Low blood pressure;
- Severe dizziness;
- Slow heartbeat;
- Slow/shallow breathing;

Other Brand Names

In some countries Zonisamide may also be known as:
- Zonegran;
- Excegran;
- Excegram;
- Exceglan;
Without Prescription (2017)