Voriconazole

 
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Without a Prescription

Voriconazole is an azole antifungal.
Voriconazole is prescribed for the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp.
Voriconazole is prescribed to treat a variety of fungal infections.
Voriconazole is particularly useful in treating Candida infections where other antifungals have failed.
Voriconazole works by killing or stopping the growth of the fungi.

Contraindications

Voriconazole is contraindicated if you have any of the following conditions:
- If you are pregnant, trying for a baby or breast-feeding;
- If you are taking any other medicines, including those available to buy without a prescription, herbal and complementary medicines;
- If you have a cancer of the blood or porphyria (a blood disorder);
- If you have any heart or heart rhythm problems;
- If you have been told you have high or low levels of potassium, calcium or magnesium in your blood;
- If you have ever had an allergic reaction to this or any other medicine;
- If you know you are at risk from pancreatitis;
- If you suffer from hypotension (low blood pressure);
- If you suffer from liver or kidney problems;
- if you are allergic to other azole antifungals (itraconazole, ketoconazole);
- if you are allergic to Voriconazole;
- if you have any other allergies;
- if you have certain hereditary problems with digesting/absorbing the sugar galactose (galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption);
- if you have heart problems (irregular heartbeat, cardiomyopathy);
- if you have liver disease;
- if you have recent chemotherapy;
- if you have untreated electrolyte imbalance (low calcium levels);

Interactions

Do not take Voriconazole with any of the following drugs:
- "blood thinners";
- "statin" drugs such as lovastatin/simvastatin;
- Amiodarone;
- Amprenavir;
- Benzodiazepines such as triazolam/alprazolam;
- Birth control pills;
- Calcium channel blockers such as felodipine;
- Carbamazepine;
- Certain barbiturates;
- Certain chemotherapy drugs such as sunitinib/dasatinib/lapatinib;
- Certain HIV non-nucleoside reverse transcriptase inhibitors;
- Certain HIV protease inhibitors;
- Cyclosporine;
- Darunavir;
- Delavirdine;
- Dihydroergotamine;
- Dofetilide;
- Drugs removed from your body by certain liver enzymes;
- Efavirenz;
- Eplerenone;
- Ergot alkaloids;
- Ergotamine;
- Macrolide antibiotics (erythromycin);
- Mephobarbital;
- Methadone;
- Nelfinavir;
- Nevirapine;
- Phenobarbital;
- Phenytoin;
- Pimozide;
- Procainamide;
- Proton pump inhibitors such as omeprazole;
- Quinidine;
- Rifabutin;
- Rifampin;
- Rifamycins;
- Ritonavir;
- Saquinavir;
- Sirolimus;
- Sotalol;
- St John's wort;
- Sulfonylureas such as glipizide/glyburide;
- Tacrolimus;
- Vinca alkaloids such as vincristine;
- Warfarin;

Side Effects

Voriconazole side effects that you should report to your health care professional or doctor as soon as possible:
- Blurred vision;
- Bone/muscle/joint pain;
- Change in the amount of urine;
- Chest/jaw/left arm pain;
- Color vision changes;
- Confusion;
- Dark urine;
- Diarrhea;
- Easy bleeding/bruising;
- Fainting;
- Fast/slow/irregular heartbeat;
- Fever;
- Headache;
- Itching/swelling (especially of the face/tongue/throat);
- Mental/mood changes;
- Muscle stiffness/spasm;
- Nausea/vomiting;
- Persistent nausea/vomiting;
- Persistent sore throat;
- Rash;
- Restlessness;
- Seizures;
- Sensitivity of eyes to light (photophobia);
- Severe dizziness;
- Signs of infection;
- Slurred speech;
- Stomach/abdominal pain;
- Swelling of the ankles/feet;
- Tiredness;
- Trouble breathing;
- Vision changes;
- Weakness;
- Yellowing eyes/skin;

Overdose

Reported Voriconazole overdose symptoms are:
- Corneal opacification;
- Other signs in mice were convulsions;
- Depressed behavior;
- Mydriasis;
- Partially closed eyes;
- Prostration;
- Salivation;
- Swollen abdomen;
- Titubation (loss of balance while moving);
Without Prescription (2017)