Vinorelbine

 
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Without a Prescription

Vinorelbine is a chemotherapy drug that works by slowing or stopping cancer cell growth.
Vinorelbine is a chemotherapy drug.
Vinorelbine is prescribed to treat cancer, like lung cancer.
Vinorelbine is prescribed to treat various types of cancer.
Vinorelbine targets fast dividing cells, like cancer cells, and causes these cells to die.

Side Effects

Vinorelbine side effects that you should report to your health care professional or doctor as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- Blood in the urine;
- breathing problems;
- Chest pain;
- constipation;
- cough;
- Decreased reflexes;
- Diarrhea;
- Dizziness;
- Easy bruising/bleeding;
- Fatigue;
- hair loss;
- Irritation at the injection site;
- Itching/swelling (especially of the face/tongue/throat);
- jaw pain;
- Joint pain;
- loss of appetite;
- low blood counts - this drug may decrease the number of white blood cells, red blood cells and platelets. you may be at increased risk for infections and bleeding;
- Mental/mood changes;
- Mouth sores;
- Muscle aches;
- nausea and vomiting;
- Nausea;
- New or increased trouble breathing;
- Numbness/tingling/pain in the hands or feet;
- pain, swelling, redness or irritation at the injection site;
- pain, tingling, numbness in the hands or feet;
- Rash;
- Severe constipation;
- Severe dizziness;
- signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, nosebleeds;
- signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness;
- signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine;
- stomach pain;
- Stomach/abdominal pain;
- Trouble breathing;
- trouble passing urine or change in the amount of urine;
- Vomiting;
- Weakness;

Contraindications

Vinorelbine is contraindicated if you have any of the following conditions:
- an unusual or allergic reaction to vinorelbine, other chemotherapy agents, other medicines, foods, dyes, or preservatives;
- blood disorders;
- breast-feeding;
- infection (especially chickenpox and herpes);
- liver disease;
- lung disease;
- nervous system disease;
- pregnant or trying to get pregnant;
- previous or current radiation therapy;
- if you are allergic to vinorelbine;
- if you have any other allergies;
- if you have blockage of the stomach/intestines (obstruction, paralytic ileus);
- if you have certain medical conditions;
- if you have decreased bone marrow function/blood cell disorders (anemia, leukopenia, thrombocytopenia);
- if you have heart disease;
- if you have liver disease;
- if you have numbness/tingling of the hands or feet;

Interactions

Do not take Vinorelbine with any of the following drugs:
- acetaminophen;
- Aprepitant;
- aspirin;
- Azole antifungals;
- Carbamazepine;
- Certain anti-seizure medicines;
- Cimetidine;
- cyclosporine;
- Drugs affecting liver enzymes that remove vinorelbine from your body;
- Erythromycin;
- fluconazole;
- ibuprofen;
- Itraconazole;
- ketoconazole;
- ketoprofen;
- Macrolide antibiotics;
- medicines for hiv like delavirdine, efavirenz, nevirapine;
- medicines for seizures like ethotoin, fosphenotoin, phenytoin;
- medicines to increase blood counts like filgrastim, pegfilgrastim, sargramostim;
- Mitomycin;
- naproxen;
- other chemotherapy drugs like cisplatin, mitomycin, paclitaxel;
- Rifabutin;
- Rifamycins;
- St John's wort;
- vaccines;
- voriconazole;
Without Prescription (2017)