Vinblastine

 
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Without a Prescription

Vinblastine is a chemotherapy drug.
Vinblastine is prescribed to treat cancer.
Vinblastine is prescribed to treat many types of cancer like breast cancer, testicular cancer, Hodgkin's disease, non-Hodgkin's lymphoma, and sarcoma.
Vinblastine slows the growth of cancer cells.
Vinblastine works by slowing or stopping the growth of cancer cells.

Side Effects

Vinblastine side effects that you should report to your health care professional or doctor as soon as possible:
- Abdominal/stomach pain;
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- Black/tarry stools;
- Bone/jaw pain;
- breathing problems;
- change in the amount of urine;
- changes in hearing;
- chest pain;
- Chest/left arm pain;
- Chills;
- Confusion;
- Constipation;
- Difficult/painful urination;
- Dizziness/feeling of spinning;
- Easy bleeding/bruising;
- Fast/pounding heartbeat;
- Fever;
- hair loss;
- Hearing problems;
- high blood pressure;
- Itching/swelling (especially of the face/tongue/throat);
- jaw pain;
- Loss of appetite;
- low blood counts - this drug may decrease the number of white blood cells, red blood cells and platelets. you may be at increased risk for infections and bleeding;
- Mental/mood changes (depression);
- mouth sores;
- nausea and vomiting;
- Nausea;
- Numbness/tingling;
- Or persistent sore throat;
- pain, swelling, redness or irritation at the injection site;
- pain, tingling, numbness in the hands or feet;
- Pain/coldness in fingers/toes;
- Pain/redness at the injection site;
- Pale/bluish fingers/toes;
- Pink/bloody urine;
- problems with balance, dizziness;
- Rash;
- Seizures;
- sensitivity to light;
- Severe dizziness;
- Severe headache;
- signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, nosebleeds;
- signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness;
- signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine;
- Slurred speech;
- stomach pain;
- Sudden shortness of breath/wheezing;
- Tiredness;
- Trouble breathing;
- tumor pain;
- Unusual lumps/skin changes;
- Vision changes;
- Vomit that looks like coffee grounds;
- Vomiting;
- Weakness on one side of the body;

Contraindications

Vinblastine is contraindicated if you have any of the following conditions:
- an unusual or allergic reaction to vinblastine, other chemotherapy agents, other medicines, foods, dyes, or preservatives;
- blood disorders;
- breast-feeding;
- dental disease;
- gout;
- infection (especially a virus infection such as chickenpox, cold sores, or herpes);
- liver disease;
- lung disease;
- nervous system disease;
- pregnant or trying to get pregnant;
- recent or ongoing radiation therapy;
- if you are allergic to vinblastine;
- if you have any other allergies;
- if you have blood vessel problems (blood clots, stroke, raynaud's disease, varicose veins);
- if you have bone marrow problems (low white count/platelets from previous chemotherapy/radiation treatment, tumor in the bone marrow);
- if you have certain medical conditions;
- if you have heart disease (angina, heart attack);
- if you have liver disease;
- if you have lung problems;
- if you have poor nutrition;
- if you have skin sores (ulcers);
- if you have stomach/intestinal sores (peptic ulcer);
- if you have untreated bacterial infection;

Interactions

Do not take Vinblastine with any of the following drugs:
- acetaminophen;
- Aminoglycosides such as gentamicin;
- Aspirin and other NSAIDs (ibuprofen);
- Aspirin;
- Azole antifungals;
- Carboplatin;
- Cisplatin;
- cyclosporine;
- Drugs affecting liver enzymes that remove vinblastine from your body;
- Drugs that may harm the ears;
- Erythromycin;
- fluconazole;
- Hydantoins (phenytoin);
- Ibuprofen;
- itraconazole;
- Ketoconazole;
- ketoprofen;
- Macrolide antibiotics;
- medicines for seizures like phenytoin;
- medicines to increase blood counts like filgrastim, pegfilgrastim, sargramostim;
- mibefradil;
- Naproxen;
- NSAIDs;
- Prepitant;
- Rifabutin;
- Rifamycins;
- Tolterodine;
- vaccines;
- verapamil;
- Voriconazole;

Overdose

Reported Vinblastine overdose symptoms are:
- Seizures;
Without Prescription (2017)