Stavudine

 
    A
    B
    C
    D
    E
    F
    G
    H
    I
    K
    L
    M
    N
    O
    P
    R
    S
    T
    U
    V
    Y
    Z

Structure

Stavudine-30 Capsules
Each capsule contains Stavudine 30 mg

Stavudine-40 Capsules
Each capsule contains Stavudine 40 mg

Without a Prescription

Stavudine is prescribed for the treatment of HIV-infected patients as part of combination therapy.

Dosage

Adults: The interval between oral doses should be 12 hours.
Stavudine may be taken without regard to meals.
The recommended starting dose based on body weight is as follows:
40 mg twice daily for patients > 60 kg
30 mg twice daily for patients < 60 kg

Paediatrics: The recommended starting dose for paediatric patients weighing less than 30 kg is 1 mg/kg/dose, given every 12 hours.
Paediatric patients weighing 30 kg or greater should receive the recommended adult dose.
Dosage adjustment: Patients should be monitored for the development of peripheral neuropathy.
Symptoms may resolve if therapy is withdrawn promptly.
In some cases, symptoms may worsen temporarily following discontinuation of therapy.
If symptoms resolve completely, resumption of treatment may be considered at half the dose.

Renal Impairment
Stavudine may be administered to adult patients with impaired renal function.

Paediatrics: There are insufficient data to recommend a specific dose adjustment of stavudine in children with renal impairment.
A reduction in the dose and/or an increase in the interval between doses should beconsidered.

Hemodialysis Patients
The recommended dose is 20 mg every 24 hours (>60 kg) or 15 mg every 24 hours (< 60 kg), administered after the completion of hemodialysis and at the same time of day on non-dialysis hours.

Contraindications

Stavudine is contraindicated in patients with clinically significant hypersensitivity to stavudine or to any of the components contained in the formulation.

Package

- Blister strip of 10 capsules;
- Container of 60 capsules;
Without Prescription (2017)