Without a Prescription

Sorafenib is prescribed to treat liver cancer and kidney cancer.
Sorafenib is a chemotherapy drug.


Sorafenib is contraindicated if you have any of the following conditions:
- If you have an unusual or allergic reaction to sorafenib, other medicines, foods, dyes, or preservatives;
- If you have bleeding problems;
- If you have breast-feeding;
- If you have heart disease;
- If you have high blood pressure;
- If you have infection (especially a virus infection such as chickenpox, cold sores, or herpes);
- If you have kidney disease;
- If you have liver disease;
- If you have pregnant or trying to get pregnant;


Do not take Sorafenib with any of the following drugs:
- Warfarin;
- St. john's wort;
- Some medicines for sleep like secobarbital;
- Rifampin;
- Rifampicin;
- Rifabutin;
- Nafcillin;
- Modafinil;
- Medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin;
- Medicines that treat blood clots like amediplase, streptokinase;
- Medicines for seizures like oxcarbazepine, phenobarbital, phenytoin;
- Irinotecan;
- Griseofulvin;
- Fluorouracil;
- Doxorubicin;
- Docetaxel;
- Dexamethasone;
- Carbamazepine;
- Bexarotene;
- Aspirin;
- Aminoglutethimide;


Sorafenib may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Sorafenib may make you feel generally unwell.
Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu.
Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant.
Do not breast-feed an infant while taking this medicine.
Do not treat yourself. Sorafenib decreases your body's ability to fight infections. Try to avoid being around people who are sick.
If you are going to have surgery or any other procedures, tell your doctor you are taking Sorafenib.
If you have any dental work done, tell your dentist you are receiving Sorafenib.
Men and women should use effective birth control while taking this medicine and for 2 weeks after stopping this medicine.
Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.
This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells.
Visit your doctor for regular check ups. You will need to have blood work while you are taking this medicine.

Side Effects

Sorafenib side effects that you should report to your health care professional or doctor as soon as possible:
- Unusually weak or tired;
- Unusual bleeding or bruising;
- Swelling in a leg;
- Stomach pain;
- Redness, blistering, peeling or loosening of the skin, including inside the mouth;
- Pain, tingling, numbness in the hands or feet;
- Nausea;
- Mouth sores;
- Loss of appetite;
- High blood pressure;
- Hair loss;
- Fever or chills, sore throat;
- Dry skin;
- Dizziness;
- Diarrhea;
- Chest pain;
- Breathing problems;
- Allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
Without Prescription (2017)