Rituximab

 
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Without a Prescription

In cancer cells, this drug targets a specific protein within cancer cells and stops the cancer cells from growing.
Rituximab changes the way the body's immune system works.
Rituximab is a monoclonal antibody.
Rituximab is a type of medication called a monoclonal antibody.
Rituximab is prescribed alone or with other medications to treat certain types of cancer (non-Hodgkin's lymphoma).
Rituximab is prescribed commonly to treat non-Hodgkin's lymphoma and other conditions.
Rituximab is prescribed for arthritis only after other medications have not worked.
Rituximab is prescribed to treat rhuematoid arthritis (RA).
Rituximab is prescribed with methotrexate to treat moderate-to-severe forms of rheumatoid arthritis.
Rituximab is prescribed with other cancer or arthritis medications.
Rituximab is prescribed with other monoclonal antibodies and radioactive drugs to treat certain cancers.
Rituximab slow the inflammatory process and help reduce joint pain and swelling.
Rituximab works by attaching to certain blood cells from your immune system (B cells) and killing them.

Side Effects

Rituximab side effects that you should report to your health care professional or doctor as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- anxiety;
- Back/joint/muscle pain;
- Black/tarry stools;
- breathing problems;
- chest pain;
- Chills;
- confused, not responsive;
- Dark urine;
- Dizziness;
- Easy bleeding/bruising;
- Extreme tiredness;
- fast, irregular heartbeat;
- feeling faint or lightheaded, falls;
- Fever;
- Flushing;
- headache;
- Heartburn;
- Increased thirst/urination;
- Itching/swelling (especially of the face/tongue/throat);
- loss of appetite;
- low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. you may be at increased risk for infections and bleeding;
- mouth sores;
- muscle aches;
- Nausea;
- night sweats;
- Painful urination;
- Persistent sore throat;
- Persistent stomach/abdominal pain;
- Rash;
- redness, blistering, peeling or loosening of the skin, including inside the mouth;
- Severe dizziness;
- Signs of an infection;
- signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine;
- signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness;
- signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine;
- stomach pain;
- swelling of the ankles, feet, or hands;
- Swelling of the hands/feet;
- Tingling of the hands/feet;
- Trouble breathing;
- trouble passing urine or change in the amount of urine;
- Vomit that looks like coffee grounds;
- Weakness;
- Yellowing eyes/skin;

Contraindications

Rituximab is contraindicated if you have any of the following conditions:
- an unusual or allergic reaction to rituximab, mouse proteins, other medicines, foods, dyes, or preservatives;
- blood disorders;
- breast-feeding;
- heart disease;
- history of hepatitis b;
- infection (especially a virus infection such as chickenpox, cold sores, or herpes);
- irregular heartbeat;
- kidney disease;
- lung or breathing disease, like asthma;
- lupus;
- pregnant or trying to get pregnant;
- if you are allergic to other mouse protein medications;
- if you are allergic to rituximab;
- if you have any other allergies;
- if you have blood disorders (thrombocytopenia);
- if you have current or returning infections;
- if you have heart problems (irregular heartbeat, angina);
- if you have lung problems (pulmonary infiltrates);
- if you have planned surgery/vaccinations;
- if you have previous severe reaction to monoclonal antibody treatment;
- if you have virus infection (chickenpox, hepatitis b or c, herpes);

Interactions

Do not take Rituximab with any of the following drugs:
- Azathioprine;
- cisplatin;
- Cis-platinum;
- Corticosteroids such as prednisone;
- Cyclosporine;
- Drugs for high blood pressure;
- Drugs that affect the immune system;
- Enalapril;
- Fludarabine;
- Measles vaccines;
- medicines for blood pressure;
- Metoprolol;
- Other anti-cancer drugs;
- Polio vaccine taken by mouth;
- Recent or planned immunizations;
- some other medicines for arthritis;
- vaccines;
- Verapamil;
Without Prescription (2017)