Rifampin

 
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Without a Script

After a 2-month period, your doctor may prescribe another combination of antituberculosis drugs (Rifamate), which can be continued for longer periods.
Rifampin is prescribed to treat the initial phase of tuberculosis.

Contraindications

Rifampin is contraindicated if you have any of the following conditions:
- if you have a history of liver disease or have had acute and painful joint swelling (gout);
- If you have a severe side effect from isoniazid (such as fever, chills, and arthritis);
- if you have an allergic reaction to rifampin, isoniazid, or pyrazinamide;
- if you have diabetes or kidney disease;
- If you have serious liver diseas;

Interactions

Do not take Rifampin with any of the following drugs:
- Tranquilizers such as Valium and Xanax;
- Theophylline (Theolair, Slo-Phyllin, Theo-Dur);
- Sulfasalazine (Azulfidine);
- Steroiddrugs such as Deltasone and Prelone;
- Progestins such as Megace;
- Probenecid (Benemid);
- Nortriptyline (Pamelor);
- Narcotic analgesics such as Darvon, Demerol, Percocet, Percodan;
- Levodopa (Sinemet);
- Ketoconazole (Nizoral);
- Itraconazole (Sporanox);
- Heart Medications such Calan, Cardizem, Lanoxin, Norpace, Mexitil, Procardia, Quinidex, and Tonocard;
- Haloperidol (Haldol);
- Fluconazole (Diflucan);
- Disulfiram (Antabuse);
- Diabetes medications such as Diabinese and Orinase;
- Dapsone;
- Cyclosporine (Sandimmune);
- Cycloserine (Seromycin);
- Cotrimoxazole (Bactrim, Septra);
- Clofibrate (Atromid-S);
- Ciprofloxacin (Cipro);
- Chloramphenicol (Chloromycetin);
- Blood Thinners such as Coumadin;
- Blood Pressure medicines such as Inderal, Tenormin, and Vasotec;
- Barbiturates such as phenobarbital and Nembutal;
- Anticonvulsants such as Dilantin, Depakene, Mysoline, Tegretol;
- Antacids such as Maalox or Tums;

Side Effects

Rifampin side effects that you should report to your health care professional or doctor as soon as possible:
- "Pins and needles" sensation in hands and feet;
- Allergy to active ingredients;
- Alteration in results of liver function tests;
- Angina (crushing chest pain);
- Anxiety;
- Bone pain;
- Chest pain;
- Chest tightness;
- Cold or flu-like symptoms;
- Cough;
- Coughing up blood;
- Decrease in the number of platelets in the blood;
- Diabetic coma;
- Diarrhea;
- Diarrhoea;
- Difficult breathing;
- Digestive pain;
- Excessive breakdown of red blood cells that reduces red blood cell count;
- Fast;
- Fluttery heartbeat;
- Headache;
- Hepatitis;
- High or persistent fever;
- Hives;
- Inflammation of the liver;
- Inflammation of the optic nerve which results in blurring of vision;
- Itching;
- Joint pain;
- Kidney failure;
- Loss of appetite;
- Loss of contact with reality;
- Nausea;
- Numbness or tingling of the legs;
- Pain in the joints;
- Rash;
- Red colouration of urine;
- Reddened skin;
- Ringing in ears;
- Seizures;
- Shortness of breath;
- Skin peeling or flaking;
- Sleeplessness;
- Sudden severe deficiency in the number of white blood cells in the blood;
- Sweating;
- Swelling of the legs;
- Vertigo;
- Vomiting;
- Yellowing of skin and eyes;
- Yellowing of the skin and eyes;

Overdose

Reported Rifampin overdose symptoms are:
- Yellow eyes and skin;
- Vomiting;
- Stupor;
- Slurring of speech;
- Shallow or difficult breathing;
- Seizures;
- Nausea;
- Liver enlargement or tenderness;
- Increasing tiredness or sluggishness;
- Hallucinations;
- Dizziness;
- Coma;
- Blurred vision;

Dosage

CHILDREN

Safety and effectiveness in children under the age of 15 have not been established.

ADULTS

Take once a day, as follows:

If you weigh 121 pounds or more: 6 tablets

If you weigh 98 to 120 pounds: 5 tablets

If you weigh 97 pounds or less: 4 tablets
Without Prescription (2017)