Procarbazine

 
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Without a Script

Because Procarbazine affects the growth of normal body cells, you will most likely experience side effects while using Procarbazine.
Procarbazine also acts as a monoamine oxidase inhibitor.
Procarbazine is an alkylating chemotherapy drug.
Procarbazine is prescribed along with other chemotherapy drugs to treat Hodgkin's disease (also known as Hodgkin's lymphoma).
Procarbazine is prescribed for use with other anticancer drugs for the treatment of stage III and stage IV Hodgkin's disease.
Procarbazine is prescribed to treat Hodgkin's disease (lymphadenoma) in combination with other medicines and for some other types of cancer.
Procarbazine is prescribed to treat other cancers such as brain tumors.
Procarbazine works by preventing cancer cells from growing and from creating new cancer cells.
Procarbazine works by preventing the growth and division of cells and therefore stops them increasing in numbers.

Contraindications

Procarbazine is contraindicated if you have any of the following conditions:
- If you are pregnant, trying for a baby or breast-feeding;
- If you are trying for a baby or intend to have children in the future regardless of your sex;
- If you have had a stroke;
- If you suffer from epilepsy or have a family history of this condition;
- If you suffer from heart disease, circulatory problems or high blood pressure;
- If you suffer from liver or kidney problems;
- If you suffer from phaeochromocytoma (a growth affecting the adrenal glands);
- if you are allergic to Procarbazine;
- if you have any other allergies;
- if you have blood diseases (bone marrow depression, low platelet counts);
- if you have current infection;
- if you have current or past tobacco use;
- if you have diabetes;
- if you have heart/blood vessel problems;
- if you have history of alcohol use;
- if you have kidney disease;
- if you have liver disease;
- if you have overactive thyroid (hyperthyroidism);
- if you have radiation therapy;
- if you have recent chickenpox;
- if you have seizures;
- if you have severe/frequent headaches;
- if you have shingles (Herpes zoster);

Interactions

Do not take Procarbazine with any of the following drugs:
- Albuterol;
- Amitriptyline/nortriptyline;
- Amphetamines;
- Antidepressants;
- Appetite suppressants;
- Apraclonidine;
- Atomoxetine;
- Azatadine;
- Brimonidine;
- Bronchodilators;
- Bupropion;
- Buspirone;
- Carbamazepine;
- Carbetapentane;
- Certain antihistamines;
- Certain drugs for glaucoma;
- Certain drugs for high blood pressure;
- Certain drugs for Parkinson's;
- Certain narcotic medications;
- Chlorpheniramine;
- Citalopram/fluoxetine/paroxetine/venlafaxine;
- Cocaine;
- Cyclobenzaprine;
- Dextromethorphan;
- Diethylpropion;
- Dopamine;
- Drugs for attention deficit disorder-ADD;
- Entacapone;
- Ephedra/ma huang;
- Epinephrine;
- Fentanyl;
- Furazolidone;
- Guanethidine;
- Herbal products;
- Isocarboxazid;
- Levodopa;
- Linezolid;
- LSD;
- MDMA/"ecstasy;
- Meperidine;
- Mescaline;
- Methyldopa;
- Methylphenidate;
- Mirtazapine;
- Moclobemide;
- Morphine;
- Nefazodone;
- Other MAO inhibitors;
- Phenelzine;
- Phenylalanine;
- Rasagiline;
- Salmeterol;
- Selegiline;
- Sibutramine;
- SSRIs;
- Stimulants;
- Street drugs;
- TCAs;
- Tolcapone;
- Tranylcypromine;

Side Effects

Procarbazine side effects that you should report to your health care professional or doctor as soon as possible:
- Black/bloody stools;
- Bloody/pink urine;
- Breathing difficulty;
- Bruising or skin rashes;
- Chest pain;
- Chills;
- Cold/clammy skin;
- Constipation;
- Cough;
- Darkening of the skin;
- Diarrhea;
- Difficult urination;
- Difficulty swallowing;
- Dizziness;
- Drowsiness;
- Dry mouth;
- Ever;
- Fainting;
- Fast or slow heartbeat;
- Feeling or being sick;
- Headache;
- Increased sweating (with or without fever);
- Itching/swelling (especially of the face/tongue/throat);
- Loss of appetite;
- Lower back or side pain;
- Mental/mood changes;
- Mouth/lip sores;
- Muscle/joint pain;
- Nausea;
- Rash;
- Seizures;
- Severe dizziness;
- Severe headache;
- Sore throat;
- Stiff/sore neck;
- Stomach pain;
- Thick mucus/phlegm;
- Tingling/numbness of hands/feet;
- Trouble breathing;
- Trouble sleeping;
- Unexpected bleeding;
- Unsteadiness;
- Unusual bleeding/bruising;
- Unusual tiredness;
- Vision problems;
- Vomit that is bloody or looks like coffee grounds;
- Vomiting;
- Yellowing eyes/skin;

Overdose

Reported Procarbazine overdose symptoms are:
- Diarrhea;
- Loss of consciousness;
- Nausea;
- Seizures;
- Severe dizziness;
- Shakiness;
- Vomiting;

Other Brand Names

In some countries Procarbazine may also be known as:
- Procarbazine;
- Nathulane;
- Natulan hydrochloride;
- Natulan;
- Natulanar;
- Natunalar;
Without Prescription (2017)