Primaquine

 
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Without a Script

Both drugs are needed for a complete cure.
Discuss the most recent information with your doctor before traveling to areas where malaria occurs.
Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver.
Primaquine is prescribed for the treatment of malaria.
Primaquine is prescribed with other medications to prevent and treat malaria caused by mosquito bites in countries where malaria is common.
Primaquine is prescribed with other medications to treat pneumocystis pneumonia (PCP) in AIDS patients.
Primaquine is used after other medications (such as chloroquine) have killed the malaria parasites living inside red blood cells.
Primaquine phosphate belongs to a class of drugs known as antimalarials.
Primaquine then kills the malaria parasites living in other body tissues.
The United States Centers for Disease Control provide updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world.
This prevents the return of the infection.

Contraindications

Primaquine is contraindicated if you have any of the following conditions:
- if you are allergic to Primaquine;
- if you have any other allergies;
- if you have blood problems (low white blood cell counts, anemia);
- if you have history of blood problems due to primaquine (hemolytic anemia, methemoglobinemia);
- if you have immune system disease (lupus, rheumatoid arthritis);
- if you have low levels of certain blood enzymes (glucose-6-phosphate dehydrogenase-G6PD, NADH methemoglobin reductase);
- if you have personal/family history of favism;

Interactions

Do not take Primaquine with any of the following drugs:
- Azathioprine;
- Drugs that may cause decreased blood cells;
- Penicillamine;
- Pyrimethamine;
- Quinacrine;
- Trimethoprim;
- Zidovudine;

Side Effects

Primaquine side effects that you should report to your health care professional or doctor as soon as possible:
- Abdominal cramps;
- Bluish skin/lips/nails;
- Brown urine;
- Chest pain;
- Confusion;
- Fast heartbeat/breathing with usual activities;
- Headache;
- High fever;
- Itching/swelling (especially of the face/tongue/throat);
- Lightheadedness;
- Methemoglobinemia;
- Nausea;
- Pale lips/nails/skin;
- Persistent sore throat;
- Rash;
- Severe chills;
- Severe dizziness;
- Severe tiredness;
- Shortness of breath;
- Signs of a certain blood problem;
- Signs of a sudden loss of red blood cells;
- Signs of serious infection;
- Stomach upset;
- Sudden pounding heartbeat;
- Trouble breathing;
- Vomiting;
- Weakness;

Overdose

Reported Primaquine overdose symptoms are:
- Seizures;
- Extreme drowsiness;
- Fast/irregular heartbeat;

Other Brand Names

In some countries Primaquine may also be known as:
- Primaquine;
- Neo-Quipenyl;
Without Prescription (2017)