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Prilosec is prescribed for the treatment of Gastric and Duodenal Ulcers, as well as Gastroesophageal reflux disease.
Prilosec is prescribed to cure patients whose ulcers are caused by infection with the germ H. pylori.
Prilosec is prescribed to treat Dyspepsia, the disease responsible for sour stomach, belching, heartburn and indigestion.
Prilosec is prescribed to treat ulcers, especially those associated with infection.
Prilosec is prescribed to treat Zollinger-Ellison Disease or the overproduction of acid in the stomach.
Prilosec medication works by treating the overproduction of acid in the stomach.

Prilosec is prescribed for:
- Duodenal ulcer (near the exit from the stomach);
- Erosive esophagitis (inflammation of the esophagus);
- For the treatment of heartburn;
- Other symptoms of gastroesophageal reflux disease (backflow of acid stomach contents into the canal leading to the stomach);
- The short-term treatment (4 to 8 weeks) of stomach ulcer;

Prilosec is prescribed to maintain healing of erosive esophagitis and for the long-term treatment of conditions in which too much stomach acid is secreted, including:
- Multiple endocrine adenomas (benign tumors);
- Systemic mastocytosis (cancerous cells);
- Zollinger-Ellison syndrome;

Side Effects

Prilosec side effects that you should report to your health care professional or doctor as soon as possible:
- Vomiting;
- Urinary tract infection;
- Upper respiratory infection;
- Unusual tiredness or weakness;
- Unusual bleeding;
- Ulcers in genitals;
- Tremors;
- Tingling or pins and needles;
- Throat pain;
- Taste distortion;
- Stomach tumors;
- Stomach pains;
- Sore throat;
- Slow heartbeat;
- Sleepiness;
- Skin inflammation;
- Ringing in ears;
- Rashes and itching;
- Rash;
- Rapid heartbeat;
- Peeling of skin;
- Painful urination;
- Pain;
- Pain in testicles;
- Nosebleeds;
- Nervousness;
- Nausea;
- Muscle cramps and pain;
- Low blood sugar;
- Loss of appetite;
- Lip ulcers, sore lips and white spots on lips;
- Leg pains;
- Joint and leg pain;
- Itching;
- Irritable colon;
- Hives;
- High blood pressure;
- Hepatitis;
- Headache;
- Hallucinations;
- Hair loss;
- General feeling of illness;
- Gas;
- Frequent urination;
- Fluttery heartbeat;
- Fluid retention and swelling;
- Fever;
- Fatigue;
- Dry skin;
- Dry mouth;
- Dizziness;
- Discolored feces;
- Difficulty sleeping;
- Diarrhea;
- Depression;
- Cough;
- Constipation;
- Confusion;
- Chest pain;
- Changes in liver function;
- Breast development in males;
- Bloody urine;
- Blood in urine;
- Blisters;
- Bleeding or crusting of lips;
- Back pains;
- Back pain;
- Apathy;
- Anxiety;
- Anemia;
- Aggression;
- Abnormal dreams;
- Abdominal swelling;
- Abdominal pain;


Prilosec is contraindicated if you have any of the following conditions:
- If a patient has any allergic reactions to Prilosec or any of its components;
- If you are allergic to certain antibiotics called macrolides;
- If you are sensitive to or have ever had an allergic reaction to Prilosec or any of its ingredients;
- If you are taking orap;
- If you have had a history of liver disease or liver problems;


Do not take Prilosec with any of the following drugs:
- Warfarin (coumadin);
- Phenytoin (dilantin);
- Ketoconazole (nizoral);
- Iron;
- Disulfiram (antabuse);
- Diazepam (valium);
- Cyclosporine (sandimmune, neoral);
- Ampicillin-containing drugs such as unasyn;
- Phenytoin;
- Diazepam;
- Anticoagulants such as coumadin;



Gastroesophageal Reflux Disease (GERD) and Acid-Related Disorders

The safety and effectiveness of Prilosec have not been studied in children under 2 years old.

For children weighing less than 44 pounds, the usual dose is 10 mg a day. For those weighing 44 pounds or more, the usual dose is 20 mg a day. For children with erosive esophagitis, your doctor will determine the correct dose based on the child's weight.

The recommended dosages are as follows:

For the treatment of gastroesophageal reflux
20 mg once daily to be taken from four to eight weeks.

For the treatment of Dyspepsia
20 mg to be taken once daily for up to 4 weeks

For the treatment of over acid production
60 mg once a day for as long as your doctor prescribed the duration.

For the treatment of gastric ulcers
40 mg a day for up to four to weeks

For the treatment of Duodenal Ulcers
20 mg to 40 mg once a day depending on your doctor's prescription

For the treatment of ulcers with infection
40 mg once a day to be taken along with clarithromycin 500 three times a day for fourteen days.


Treatment of Duodenal Ulcers Caused by H. Pylori

In combination therapy with Biaxin alone, the usual dosage is 40 mg of Prilosec once daily and 500 mg of Biaxin 3 times a day for 14 days, followed by 20 mg of Prilosec once daily for an additional 14 days.

If amoxicillin is included in the treatment, the recommended dosage is 20 mg of Prilosec, 500 mg of Biaxin, and 1,000 mg of amoxicillin twice a day for 10 days, followed by 20 mg of Prilosec once daily for an additional 18 days.

Short-term Treatment of Active Duodenal Ulcer

The usual dose is 20 mg once a day. Most people heal within 4 weeks, although some require an additional 4 weeks of Prilosec therapy.

Gastric Ulcer

The usual dose is 40 mg once a day for 4 to 8 weeks.

Pathological Hypersecretory Conditions

The usual starting dose is 60 mg once a day. If you take more than 80 mg a day, your doctor will divide the total into smaller doses. The dosing will be based on your needs.

Gastroesophageal Reflux Disease (GERD)

The usual dose for people with symptoms of GERD is 20 mg daily for up to 4 weeks. For erosive esophagitis accompanied by GERD symptoms, the usual dose is 20 mg a day for 4 to 8 weeks.

The dose may be continued to maintain healing.


Reported Prilosec overdose symptoms are:
- Vomiting;
- Sweating;
- Rapid heartbeat;
- Nausea;
- Headache;
- Flushing;
- Dry mouth;
- Drowsiness;
- Confusion;
- Blurred vision;

Other Brand Names

- Gastroguard;
- Logastric;
- Omeprazen;
- Omeprazole;
- Pepticum;
- Prilosec;
- Zoltum;
Without Prescription (2017)