Prazosin

 
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Structure

Prazosin-1 Tablets
Each tablet contains Prazosin hydrochloride 1 mg

Prazosin-2.5 Tablets
Each extended release tablet contains Prazosin hydrochloride 2.5 mg

Prazosin-5 Tablets
Each extended release tablet contains Prazosin hydrochloride 5 mg

Without a Script

Prazosin is prescribed for:
- All grades of hypertension;
- Benign prostatic hyperplasia;
- Moderate to severe congestive heart failure;
- Raynaudís phenomenon and raynaudís disease;

Dosage

Hypertension
Prazosin can be used either alone or in combination with other anti-hypertensive drugs.
Treatment is started with a dose of 0.5 mg twice daily or three times daily for 3-7 days.
Patients should be advised to take the first dose before going to bed at night because the first dose of prazosin may cause a marked postural hypotension, although this is unusual with a starting dose of 0.5 mg.
The dose may then be increased to 1 mg twice daily or three times daily over the next 3-7 days.
Thereafter the dose should be gradually adjusted according to the patientís individual blood pressure response.
Daily doses greater than 20 mg are not recommended.
The antihypertensive efficacy of prazosin can be potentiated by adding a mild diuretic such as a thiazide.
The above dosage schedule may be employed when prazosin is added to other antihypertensive drugs (such as b-adrenoceptor blockers or angiotensin-converting enzyme inhibitors), which have not adequately controlled blood pressure.
In this case the dose of the first agent is sometimes reduced to a maintenance level before adding prazosin.

Contraindications

Prazosin is contraindicated if you have any of the following conditions:
The only absolute contraindication is sensitivity to prazosin or related quinazolines.

Package

- Tablets Blister of 10;
- Tablets Blister of 15;
Without Prescription (2017)