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Piperacillin-Tazobactam is a drug normally prescribed in the treatment of various types of infections caused by bacteria. This type of drug works killing the harmful bacteria before it starts spreading in the patient's body. Piperacillin-Tazobactam is a penicillin drug. There are many types of penicillin drugs, but each of them are prescribed for different purposes (one can not use a certain kind of penicillin in another one's place). Piperacillin-Tazobactam can be combined with other drugs that fight bacteria, but it has no effect in the case of colds, flu or any other infections caused by viruses.
Piperacillin-Tazobactam is a penicillin drug. Therefore, it is usually prescribed to treat patients who are suffering from bacterial infections. Piperacillin-Tazobactam cannot treat viral infections, but it can be prescribed for other purposes that have not been mentioned here.


Before you start taking Piperacillin-Tazobactam you should inform your doctor if you have:
- Pregnancy- Piperacillin-Tazobactam has not been tested on pregnant women. however, most penicillin drugs do not harm the growing fetus if taken during pregnancy. in any case, it is best that you discuss it with your doctor before starting to take Piperacillin-Tazobactam if you are pregnant or are planning to be so soon;
- Older adults- most penicillin drugs and even some beta-lactamase inhibitors should not have harmful effects when given to elderly patients. they are not known to affect them in different ways than they affect adults;
- Diet- you doctor should know if you are following a low-sodium (that means low-salt) diet. among Piperacillin-Tazobactam's, and some other penicillin drugs' ingredients there can be enough sodium that could have harmful effects on some patients;
- Children- most penicillin drugs and also beta-lactamase inhibitors can be prescribed to children, because they are not known to affect them in different ways than they affect adults;
- Breast-feeding- most penicillin drugs and also sulbactam (that is a beta-lactamase inhibitor), can and do pass into the patient's breast milk. this might affect the nursing infant (side effects such as skin rash, diarrhea, fungus infections are known to occur). therefore, you should ask your doctor if it is safe to take Piperacillin-Tazobactam if you are nursing an infant;
- Allergies- you must tell your personal physician if you are suffering from allergic reactions to penicillins, beta-lactamase inhibitors or cephalosporins. you should inform your doctor if you are allergic to foods, dyes or preservatives, or to any other substances;

Intake Guidelines

Ask your doctor how and when you should take Piperacillin-Tazobactam. You ought to properly follow all his instructions. If you fail to understand some of them, you should ask a doctor, a pharmacist or a nurse for further explanations.


Piperacillin-Tazobactam dose (like the dose of any other penicillin drug) varies from one person to another. Therefore, you should ask your doctor to tell you the dose of Piperacillin-Tazobactam that you should take in. You can also rely on the instructions on the drug's label, which usually gives you the average dose of Piperacillin-Tazobactam.


In order to avoid Piperacillin-Tazobactam overdose, you should take the exact dose of Piperacillin-Tazobactam that your doctor has prescribed you (you could measure the exact amount of Piperacillin-Tazobactam by using a measuring device - a measuring cup or a measuring spoon). If you suspect that you might be suffering from an overdose with Piperacillin-Tazobactam, you should seek medical care. Contact your local poison control center as soon as you can. Alert your personal doctor immediately.

Missed Dose

In order to get the best results from your treatment with Piperacillin-Tazobactam, you should take it on a regular basis. If you miss one of your Piperacillin-Tazobactam doses, ask your doctor for further instructions. Do not take a double dose of Piperacillin-Tazobactam without your physician's consent.

Side Effects

Beside his benefic effects, a treatment with Piperacillin-Tazobactam can result in some dangerous or bothersome side effects. During your treatment with Piperacillin-Tazobactam you may experience some dangerous, but rare, side effects such as cough; fever; irregular or fast irregular breathing; sudden fainting or lightheadedness; joint pain; redness, swelling or pain at the injection's site; swelling or puffiness around the face; irritated or red eyes ; breath shortness; itching, hives, skin rash; sore tongue or mouth; abnormal weakness or tiredness; vaginal discharge and vaginal itching; white patches on your tongue or in your mouth. More common side effects are diarrhea, gas, headaches, etc.
If you experience anything unusual during your treatment with Piperacillin-Tazobactam, you should alert your doctor immediately.


Inform your doctor before you start taking any of these drugs during your Piperacillin-Tazobactam treatment:
- Anticoagulants;
- Dipyridamole;
- Divalproex;
- Heparin;
- Oral contraceptives;
- Pain or inflammation medicine;
- Pentoxifylline;
- Plicamycin;
- Probenecid;
- Sulfinpyrazone;
- Valproic acid;

In case you need to combine any of the drugs that have been listed here with Piperacillin-Tazobactam, you might need to take in a lower dose (your doctor will make the necessary adjustments to it), or you might need to stop your treatment with Piperacillin-Tazobactam. You should inform your doctor if you are planning to take any other drugs beside Piperacillin-Tazobactam, even if they are simple cold, flu or cough medicines, herbal products, minerals and vitamins.

Other Brand Names

In some countries Piperacillin-Tazobactam may also be known as:
- Cilpier;
- Diperil;
- Ecosette;
- Farecillin;
- Pentcillin;
- Perasint;
- Pipetexina;
- Pipraks;
- Pipril;
- Reparcillin;
- Semipenil;
- Sintoplus;
- Tazobac;
- Tazobax;
- Tazonam;
- Tazoxil;
- Zobactam;
- Zoracilin;
Without Prescription (2017)