Without a Prescription

Antihistamines reduce itching and swelling and dry up secretions from the nose, eyes, and throat.
Antihistamines work by decreasing the effects of histamine, a chemical the body releases in response to certain irritants. Histamine narrows air passages in the lungs and contributes to inflammation.
Children should be carefully supervised while they are bike-riding, roller-skating, or playing until the drug's effect on them is established.
It is used, with other medications, for pain after surgery.
Phenergan is an antihistamine that relieves nasal stuffiness and inflammation and red, inflamed eyes caused by hay fever and other allergies.
Phenergan is prescribed as a sedative and sleep aid for both children and adults, and is prescribed to prevent and control nausea and vomiting before and after surgery and to prevent and treat motion sickness.
Phenergan may cause considerable drowsiness.
You should not drive or operate dangerous machinery or participate in any hazardous activity that requires full mental alertness until you know how you react to Phenergan.

It is prescribed to treat:
- Allergic reactions to blood transfusions;
- Itching swelling and redness from hives and other rashes;
- With other medications anaphylactic shock (severe allergic reaction);

Side Effects

Phenergan side effects that you should report to your health care professional or doctor as soon as possible:

Side effects may include:
- Yellow skin and eyes;
- Vomiting;
- Unnaturally good mood;
- Tremors;
- Swollen face and throat;
- Sweating;
- Stiff neck;
- Slow heartbeat;
- Sleepiness;
- Sensitivity to light;
- Seizures;
- Sedation (extreme calm);
- Ringing in the ears;
- Rigid muscles;
- Rash;
- Rapid heartbeat;
- Protruding tongue;
- Nightmares;
- Nervousness;
- Nausea;
- Nasal stuffiness;
- Loss of movement;
- Lack of energy;
- Lack of coordination;
- Irregular heartbeat;
- Insomnia;
- Impaired or interrupted breathing;
- Hysteria;
- Hives;
- Hallucinations;
- Fever;
- Fatigue;
- Faintness;
- Excitement;
- Dry mouth;
- Double vision;
- Dizziness;
- Disorientation;
- Confusion;
- Changes in blood pressure;
- Blurred vision;
- Blood disorders;
- Asthma;
- Agitation;
- Abnormal eye movements;


Phenergan is contraindicated if you have any of the following conditions:
- If you are taking other medications that cause sedation;
- If you have a seizure disorder;
- If you have any uncontrolled movements or seem to be unusually sensitive to sunlight;
- If you have chronic breathing problems such as emphysema;
- If you have ever had an allergic reaction to it or to related medications, such as thorazine, mellaril, stelazine, or prolixin;
- If you have heart disease, high blood pressure or circulatory problems, liver problems, the eye condition called narrow-angle glaucoma, peptic ulcer or other abdominal obstructions, or urinary bladder obstruction due to an enlarged prostate;
- If you suffer from sleep apnea (periods during sleep when breathing stops);


Do not take Phenergan with any of the following drugs:
- Tranquilizers such as xanax and valium;
- Sedatives such as halcion, dalmane, and seconal;
- Narcotic pain relievers such as demerol and dilaudid;
- Mao inhibitors such as the antidepressants nardil and parnate;
- Drugs that reduce bone-marrow function (certain cancer drugs);
- Drugs that control spasms, such as cogentin;
- Certain antidepressant drugs, including elavil and tofranil;




The usual dose is a single 25-milligram dose at bedtime, or 6.25 to 12.5 milligrams 3 times daily.


The average oral dose is 25 milligrams taken before bed however, your doctor may have you take 12.5 milligrams before meals and before bed.



The usual dose is 12.5 to 25 milligrams by tablets or rectal suppository at bedtime.


The usual dose is 25 to 50 milligrams for nighttime sedation.

Older Adults

The dosage is usually reduced for people over 60.


The average dose of Phenergan for nausea and vomiting in children or adults is 25 milligrams.
Your doctor may have you take 12.5 to 25 milligrams every 4 to 6 hours, if necessary.
When oral medication cannot be tolerated, use the rectal suppository.
Phenergan and other anti-vomiting drugs should not be given to children if the cause of the problem is unknown.
For nausea and vomiting in children, the dose is usually calculated at 0.5 milligram per pound of body weight and will be based on the age of the child and the severity of the condition being treated.



The usual dose of Phenergan tablets, syrup, or rectal suppositories is 12.5 to 25 milligrams taken twice a day.


The first dose should be taken one-half to 1 hour before you plan to travel, and the second dose 8 to 12 hours later, if necessary.
The average adult dose is 25 milligrams taken twice daily.
On travel days after that, the recommended dose is 25 milligrams when you get up and again before the evening meal.


Symptoms of Phenergan overdose may include:
- Writhing movements;
- Very low blood pressure;
- Stomach and intestinal problems;
- Slowed heartbeat;
- Slowdown in brain activity;
- Seizures;
- Poor coordination;
- Muscle tension;
- Loss of consciousness;
- Heightened reflexes;
- Flushing;
- Fixed and dilated pupils;
- Dry mouth;
- Difficulty breathing;
Without Prescription (2017)