Parlodel

 
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Without a Prescription

Parlodel mimics the action of dopamine, a chemical lacking in the brain of someone with Parkinson's disease.
Parlodel inhibits the secretion of the hormone prolactin from the pituitary gland.

Parlodel is prescribed to treat a variety of medical conditions, including:
- Pituitary gland tumors;
- Parkinson's disease;
- Menstrual problems such as the abnormal stoppage or absence of flow, with or without excessive production of milk;
- Infertility in some women;
- Growth hormone overproduction leading to acromegaly, a condition characterized by an abnormally large skull, jaw, hands, and feet;

Parlodel is prescribed for:
- Benign breast disease or breast pain that occurs at certain times of the menstrual cycle;
- Benign tumours in the pituitary gland that release prolactin;
- Excess growth hormone production resulting in enlarged facial features, hands and feet;
- High prolactin levels that have caused suppression of the sexual glands and/or abnormal milk production in men or women;
- Infertility;
- Menstrual cycle disorders and premenstrual symptoms, eg headaches, breast pain, mood changes or bloating;
- Parkinson's disease;
- Preventing or stopping milk production for medical reasons following childbirth, miscarriage or abortion;

Contraindications

Parlodel is contraindicated if you have any of the following conditions:
- if you are allergic to Parlodel or to any other drugs containing ergot alkaloids, such as Bellergal-S and Cafergot;
- If you are being treated for Parkinson's disease;
- If you are being treated with Parlodel for endocrine problems related to a tumor and stop taking this medication;
- if you are pregnant (unless your doctor finds it medically necessary);
- If you experience a persistent watery nasal discharge while taking Parlodel;
- If you have an abnormal heartbeat rhythm caused by a previous heart attack;
- if you have high blood pressure that is not under contro;
- If you have kidney or liver disease;
- if you have mental problems, any disease of the heart and circulatory system, peptic ulcer, or bleeding in the stomach and intestines;

Interactions

Do not take Parlodel with any of the following drugs:
- Pimozide (Orap);
- Other Ergot derivatives such as Hydergine;
- Oral Contraceptives;
- Metoclopramide (Reglan);
- Blood Pressure-lowering drugs such as Aldomet and Catapres;

Side Effects

Parlodel side effects that you should report to your health care professional or doctor as soon as possible:
- Abdominal bleeding;
- Abdominal cramps or discomfort;
- Abnormal heart rhythm;
- Anxiety;
- Bleeding or ulceration of the stomach or intestine;
- Blurred vision or temporary blindness;
- Cold feet;
- Confusion;
- Constipation;
- Constipation;
- Depression;
- Diarrhea;
- Difficulty performing voluntary movements, resulting in jerky or involuntary movements or muscle twitches;
- Difficulty swallowing;
- Dizziness;
- Drop in blood pressure when moving from lying or sitting to sitting or standing;
- Drop in blood pressure;
- Drowsiness;
- Dry mouth;
- Fainting;
- Fast or slow heartbeat;
- Fatigue;
- Fibrous thickening of the lining that covers internal organs including the kidneys, the heart or the lungs;
- Frequent urination;
- Hair loss;
- Hallucinations (particularly in Parkinson's patients);
- Hallucinations;
- Headache;
- Heart attack;
- Heavy-headedness;
- Inability to hold urine;
- Inability to sleep;
- Inability to urinate;
- Increase in blood pressure;
- Indigestion;
- Leg cramps;
- Light-headedness;
- Loss of appetite;
- Loss of coordination;
- Lower back pain;
- Muscle cramps in feet and legs;
- Muscle cramps;
- Nasal congestion;
- Nausea and vomiting;
- Nausea;
- Nervousness;
- Nightmares;
- Numbness;
- Pale face;
- Paranoia;
- Prickling or tingling;
- Rash;
- Reduced tolerance to cold;
- Seizures;
- Severe or continuous headache;
- Shortness of breath;
- Sluggishness;
- Splotchy skin;
- Stroke;
- Swelling in feet and ankles;
- Tingling of ears or fingers;
- Twitching of eyelids;
- Uncontrolled body movement;
- Vertigo;
- Visual disturbance;
- Vomiting;
- Weakness;

Overdose

Reported Parlodel overdose symptoms are:
- Yawning repeatedly;
- Vomiting;
- Sweating;
- Severely low blood pressure;
- Pallor;
- Nausea;
- Lethargy;
- Hallucinations;
- Feeling unwell;
- Drowsiness;
- Dizziness;
- Delusions;
- Constipation;
- Confusion;

Dosage

CHILDREN

The safety and effectiveness of Parlodel have not been established in children.

ADULTS

Dosage information given is for 2.5-milligram tablets.

Parlodel is available as 2.5-milligram tablets and 5-milligram capsules.

Parkinson's Disease

The usual starting dose of Parlodel is one-half tablet twice a day with meals.

Parlodel taken in combination with levodopa may provide additional treatment benefits if you are currently taking high doses of levodopa, are beginning to develop a tolerance to levodopa, or are experiencing "end of dose failure" on levodopa therapy.

If necessary, your doctor may increase the dose every 14 to 28 days by 1 tablet per day.

Your dose will be monitored by your doctor at 2-week intervals.

Growth Hormone Overproduction

The dose should not exceed 100 milligrams per day. Your doctor will do a monthly re-evaluation.

Treatment for the overproduction of growth hormones is usually one-half to 1 tablet with food at bedtime for 3 days. Your doctor may add one-half to 1 tablet every 3 to 7 days. The usual treatment dose varies from 20 to 30 milligrams per day.

Excess Prolactin Hormone

The usual longer term dose is 5 to 7.5 milligrams per day and ranges from 2.5 to 15 milligrams per day.

If you are being treated for conditions associated with excess prolactin, such as menstrual problems, with or without excessive milk production, infertility, or pituitary gland tumors, the usual starting dose is one-half to 1 tablet daily. Your doctor may add a tablet every 3 to 7 days, until the treatment works.
Without Prescription (2017)