Without a Prescription

Most physicians are familiar with Pancrelipase. This enzyme combination contains protease, lipase, and amylase, proteins that are naturally produced by the pancreas of a healthy organism. These enzymes play an important part in digesting sugars, proteins and fats. If a patient's organism fails to produce the necessary amount of these proteins, he or she should start using Pancrelipase (or any other similar medicine) in order to replace them.
Several medical issues require a treatment with Pancrelipase. Among the most common, are: chronic pancreatic inflammation, cystic fibrosis, pancreatic ducts blockage and so on.


Some medical conditions such as the following do not respond well to a therapy with Pancrelipase:
- Allergic reactions to pork products;
- Acute pancreatitis;

Patients who suffer from any of these medical issues are generally not allowed to start a therapy with Pancrelipase. However, exceptions can be made (if a treatment with Pancrelipase is vital for the patient's life). In such cases, the patient is given lower doses of Pancrelipase under strict medical supervision (hospitalization is sometimes required).

Intake Guidelines

Even if a therapy with Pancrelipase could trigger severe adverse reactions, these could be avoided if you take it properly. This is why we recommend all patients who want to use Pancrelipase to discuss with an authorized medical provider and work up a both effective and safe treatment schedule. If you have any further questions regarding the intake of Pancrelipase (this includes proper administration method and other similar questions) you should ask for your physician's assistance. The drug's label is considered helpful by many patients who want to know more about Pancrelipase.
A dose of Pancrelipase should be taken in either during or before a main meal (or at least a heavier snack). The capsule contents or the tablets must not be held in your mouth, as this could trigger severe irritation. Each patient must try to swallow the pills as a whole (crushing, breaking or chewing them are also strictly forbidden), as every pill of Pancrelipase has been especially designed to gradually release its ingredients inside the patient's organism.
If it is impossible for a patient to swallow the entire Pancrelipase pill, he or she may open some forms of Pancrelipase and then sprinkle their content on pudding, applesauce, or other forms of soft foods. Follow your soft food with a glass of liquid, in order to ensure that you have swallowed all the medicine. Your physician will be happy to point you to the proper form of Pancrelipase that you ought to take in.
The powder that can be found inside the capsules of Pancrelipase can be dangerous. No patient must let it come into direct contact with his or her skin, as this could trigger further severe irritations. If inhaled, the powder can also trigger unpleasant lung damage.


The safest and easiest way to acquire the appropriate dosing instructions during your therapy with Pancrelipase is to consult your doctor, or another health care professional (at the beginning of your therapy with it). If you are unhappy with your initial dose of Pancrelipase, and you feel it needs to be altered, you should seek further medical assistance. You are not allowed to make any changes to this dose without your doctor's direct approval.


An overdose with Pancrelipase can have severe effects if it is not treated in time by a professional, in an authorized medical setting. Patients who suspect having over dosed with Pancrelipase should seek medical attention as soon as they can. The average symptoms that are triggered by the intake of extremely high doses of Pancrelipase include stomach upset, nausea and so on.

Missed Dose

If you want to have a healthy and safe experience with Pancrelipase you should follow the treatment schedule that you and your personal doctor have established at the beginning of your intake of Pancrelipase. In case that a missed dose happens to occur, you should seek your physician's advice. If you are unhappy with the dosing schedule that you are currently on, you should change it (make sure that you do so under your physician's direct supervision). Double doses of Pancrelipase are strictly forbidden.

Side Effects

All patients who are following a therapy with Pancrelipase ought to immediately stop their intake of Pancrelipase and look for professional medical care if they start to suffer from the signs that usually point to a severe allergic reaction to Pancrelipase.
A prolonged therapy with Pancrelipase can also trigger a set of other side effects (adverse reactions) that are not as severe as those listed above. They include:
- Constipation and / or diarrhea;
- Flatulence;
- Greasy stools;
- Lung or skin irritation;
- Pain, abdominal discomfort cramping;
- Perianal irritation;
- Vomiting and / or nausea;


Even if Pancrelipase is considered to be a quite safe remedy, as it has not known harmful interactions with other medications, we recommend all patients who are following a therapy with Pancrelipase to avoid using other prescription or non prescription drugs that are based on the same ingredients or that achieve the same purpose. More information about possible drug interactions can be found at any pharmacy.

Other Brand Names

In some countries Pancrelipase may also be known as:
- Bilipeptal Mono;
- Bioglan Panazyme;
- Cholspasminase N;
- Clen-Zym;
- Cotazym S Forte;
- Cotazym;
- Cotazym;
- Fermento duodenal;
- Festal N;
- Festal;
- Gastrix;
- Kreon;
- Lipancrea;
- Lipazym;
- Mezym F;
- Neo-Pancreatinum;
- Neo-Panpur;
- Opti-Free Enzymatic;
- Opti-Free Supraclens;
- Opti-Plus;
- Opti-Zyme;
- Orozim;
- Ozym;
- Palcaps;
- PAN-2400;
- Pancrease;
- Pancrecarb;
- Pancreolan;
- Pancrin;
- Pangrol;
- Pankreatan;
- Pankreon forte;
- Panzynorm forte-N;
- Panzynorm;
- Panzytrat;
- Polyzym;
- Prolipase;
- Selecto;
- Ultrase;
- Unexym mono;
- Viokase;
- Vision Care Enzymatic Cleaner;
Without Prescription (2017)