Oxaliplatin

 
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Contraindications

Oxaliplatin is contraindicated if you have any of the following conditions:
- an unusual or allergic reaction to oxaliplatin, other chemotherapy, other medicines, foods, dyes, or preservatives;
- breast-feeding;
- kidney disease;
- pregnant or trying to get pregnant;
- if you are allergic to other platinum-containing products (cisplatin, carboplatin);
- if you are allergic to Oxaliplatin;
- if you have any other allergies;
- if you have blood disorders;
- if you have bone marrow problems;
- if you have kidney problems;
- if you have nerve disorders;

Without a Prescription

Oxaliplatin is a chemotherapy drug that contains platinum.
Oxaliplatin is a chemotherapy drug.
Oxaliplatin is prescribed in combination with other medications to slow or stop cancer cell growth.
Oxaliplatin is prescribed to treat advanced cancer of the colon and rectum.
Oxaliplatin is prescribed to treat cancers of the colon and rectum, and many other cancers.
Oxaliplatin targets fast dividing cells, like cancer cells, and causes these cells to die.

Overdose

Reported Oxaliplatin overdose symptoms are:
- Chest pain;
- Numbness/tingling of the arms/legs;
- Severe vomiting;
- Shortness of breath;
- Very slow heartbeat;
- Wheezing;

Interactions

Do not take Oxaliplatin with any of the following drugs:
- acetaminophen;
- aspirin;
- ibuprofen;
- ketoprofen;
- medicines to increase blood counts like filgrastim, pegfilgrastim, sargramostim;
- naproxen;
- probenecid;
- some antibiotics like amikacin, gentamicin, neomycin, polymyxin b, streptomycin, tobramycin;
- zalcitabine;
- amikacin;
- aminoglycosides;
- amphotericin b;
- cyclosporine;
- gentamicin;
- nalidixic acid;
- nonsteroidal anti-inflammatory drugs (ibuprofen);
- tacrolimus;
- vancomycin;

Side Effects

Oxaliplatin side effects that you should report to your health care professional or doctor as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- breathing problems;
- changes in vision;
- chest pain, pressure;
- constipation;
- cough;
- diarrhea;
- hair loss;
- jaw tightness;
- loss of appetite;
- low blood counts - this drug may decrease the number of white blood cells, red blood cells and platelets. you may be at increased risk for infections and bleeding;
- metallic taste in the mouth or changes in taste;
- mouth sores;
- nausea and vomiting;
- pain, swelling, redness or irritation at the injection site;
- pain, tingling, numbness in the hands or feet;
- problems with balance, talking, walking;
- redness, blistering, peeling or loosening of the skin, including inside the mouth;
- signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, nosebleeds;
- signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness;
- signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine;
- stomach pain;
- trouble passing urine or change in the amount of urine;
- black stools;
- changes in taste;
- chest pain;
- chest pressure;
- decreased urination;
- diarrhea;
- dizziness;
- dry cough;
- dry mouth;
- easy or unusual bruising/bleeding;
- eye pain;
- fainting;
- groin/calf pain;
- headache;
- increased thirst;
- itching/swelling (especially of the face/tongue/throat);
- jaw tightness;
- mental/mood changes (depression);
- mouth sores;
- muscle cramps;
- nosebleeds;
- numbness/tingling/"pins and needles" sensation of the hands/feet/mouth/throat;
- pain/redness/swelling at the injection site;
- pain/redness/swelling of the arms/legs;
- rash;
- seizures;
- sensitivity to cold;
- severe dizziness;
- shortness of breath;
- signs of too much body water loss;
- strange feeling in your tongue;
- sudden confusion;
- tiredness;
- trouble breathing;
- trouble breathing/swallowing/speaking;
- trouble sleeping;
- vision changes (temporary vision loss);
- vomit that looks like coffee grounds;
- weakness;
Without Prescription (2017)