Without a Prescription
Orlistat blocks absorption of dietary fat into the bloodstream, thereby reducing the number of calories you get from a meal. At the usual dosage level, it cuts fat absorption by almost one-third. Combined with a low-calorie diet, it is prescribed to promote weight loss and discourage the return of unwanted pounds.
Orlistat capsules contain the active ingredient orlistat, which is a type of drug called a lipase inhibitor. It is prescribed to aid weight loss in people who are obese.
Orlistat is prescribed for obese individuals and for overweight people who have other health problems such as high blood pressure, diabetes, or high cholesterol levels. Your weight status is determined by your body mass index (BMI), a comparison of height to weight.
Orlistat is prescribed for the treatment of obesity.
Orlistat is prescribed to aid weight loss in obese people who have a body mass index of 30kg/m or more. It can be prescribed to overweight people who have a BMI of 28kg/m? or more, if they have additional risk factors for obesity-related diseases.
Orlistat is not absorbed into the bloodstream, but works locally in the stomach and small intestine, where it prevents the action of two compounds found in the digestive juices. These compounds are called gastric and pancreatic lipases. They normally break down fats that we consume in our diet.
Orlistat should be prescribed in conjunction with a mildly low calorie diet. Ask your doctor, pharmacist or dietician for advice on what to eat while taking orlistat. Your doctor may ask you to stop treatment if you have been unable to lose at least five per cent of your body weight after 12 weeks of treatment.
Orlistat works by preventing gastric and pancreatic lipases from working. It is taken at mealtimes to prevent fat that is eaten in the meals from being broken down and absorbed by the body. This means the body cannot use the fat as a source of energy, or convert it into fat tissue. Instead, the fat is excreted in the faeces. This helps weight loss.
The fats we consume in our diets are made of molecules that are too large to be absorbed from the gut into the bloodstream. They need to be broken down into smaller molecules during the process of digestion, in order to be absorbed into the bloodstream. Gastric and pancreatic lipases are the compounds in the gut that carry out this function.
Orlistat side effects that you should report to your health care professional or doctor as soon as possible:
- Abdominal discomfort or pain;
- Abdominal pain or discomfort;
- Back pain;
- Faecal incontinence;
- Fatty or oily stools;
- Fecal urgency or incontinence;
- Flatulence with discharge;
- Gall stones;
- Gas with fecal discharge;
- Gum problems;
- Increased defecation;
- Infections of the airways;
- Inflammation of the liver;
- Irregular menstrual cycle;
- Low blood sugar levels in people with diabetes;
- Menstrual problems;
- Muscle pain;
- Oily discharge;
- Oily or fatty stools;
- Oily spotting from the rectum;
- Pain or discomfort in the rectum;
- Raised liver enzymes;
- Rectal discomfort or pain;
- Respiratory tract infections;
- Skin rash;
- Sleep problems;
- Tooth or gum disorders;
- Tooth problems;
- Urgent or increased need to open the bowels;
- Urinary tract infection;
- Urinary tract infections;
- Vaginal inflammation;
Side effects that usually occur after the first year of treatment with Orlistat include:
- Swollen feet;
- Leg pain;
ADULTS AND CHILDREN 12 YEARS AND OLDER
The recommended dose is one 120-mg capsule 3 times daily with each main meal containing fat.