Without a Prescription

Nicorandil is a pharmaceutical product from the potassium channel openers class of medication. It acts by increasing the amount of potassium that leaves certain muscle cells (in particular, those found in blood vessels), allowing the blood vessels to widen and thus easing the blood flow. Also, Nicorandil has a relaxing effect on the smooth muscles of the blood vessels.
Nicorandil is commonly prescribed for the treatment of patients that are suffering from chronic stable angina pectoris, either in monotherapy or in combination with other pharmaceutical agents. Health care professionals may decide to employ Nicorandil in the treatment of other medical affections that are not listed here as well; if you have received a prescription for Nicorandil and are not sure why it has been prescribed to you, it is best to consult with your personal physician as he or she is able to provide you with additional information.


You may not take Nicorandil if you have a known or suspected allergy to any of the ingredients of Nicorandil; if you are not sure if you are allergic to any of the ingredient substances of this pharmaceutical preparation, consult with your personal health care specialist.
You may not take Nicorandil if you are suffering from hypotension or if you also have other cardiac affections. Hepatic impairment may affect your ability to start a treatment course with this pharmaceutical product. Make sure that the prescriber is familiar with your current health state as well as with your medical history before starting a therapy course with Nicorandil.
If you are pregnant or if you are breast feeding a baby, you should consult with your personal physician regarding the possible benefits and risks of the Nicorandil therapy. At this time it is not known if Nicorandil may affect an unborn child or a nursing infant.

Intake Guidelines

Your prescriber will provide a detailed list of Nicorandil intake guidelines. It is best that you closely follow his or her directions in order to obtain the best therapeutic effects from the treatment.
Typically, you will need to take Nicorandil twice per day (once in the morning and again in the evening). Swallow the tablets whole, without chewing, crushing or breaking them. If you have trouble swallowing the tablets or if you experience stomach upset, you may take the medication doses with food or water.


The exact Nicorandil dosage that you will need to employ for the duration of your therapy depends on the condition that is being treated as well as on a number of other factors. These may vary greatly from one patient to another, causing the dosage to differ from one case to another as well. It is strongly recommended that you do not use the medication dosage that has been prescribed to another patient, as this may cause the therapy results to be different than expected. The usual dosage prescribed to adult patients is of 10 to 20 mg taken twice daily.
If you are not sure what the Nicorandil dosage that you should employ is, you should consult with your personal health care professional.


Taking large quantities of Nicorandil or taking the medicine for prolonged periods of time may result in an overdose with this pharmaceutical product. An overdose is a serious medical condition which may cause a number of severe short and long term consequences on your general health state. As such, it is strongly recommended that you do not exceed the prescribed medication dosage and do not take Nicorandil for longer than your prescriber has directed.
If you believe that you may be affected by an overdose with Nicorandil, you should go to the nearest clinic or hospital in order to receive emergency medical attention. Alternatively, call the local or regional poisons center or contact your personal health care professional.

Missed Dose

It is recommended that you set up a strict intake schedule for your Nicorandil doses. The best results are obtained when the medicine is taken at around the same time each day - this also helps reduce the chances of accidentally missing any medicine doses. You may ask your personal physician to assist you in setting up the intake schedule, and it is advised that you also take into account your daily agenda and your lifestyle particularities.
If you accidentally miss one of the Nicorandil doses, take it as soon as you remember about it. However, you should skip the missed dose if it is almost time for another intake of the medicine. If you miss more than one dose or if you are not sure what to do, seek the advice of your health care professional.

Side Effects

Patients following a therapy course with Nicorandil may experience a number of mild to severe side effects. In most cases, when present, the adverse reactions are mild and go away after a few days; such symptoms as stomach pain, indigestion, nausea, breathing difficulties, coughing, dizziness, tiredness, flushing, irregular or fast heartbeat, hypertension and muscular or back pains have been reported in such situations.
Allergic reactions are among the most severe side effects that may occur during your Nicorandil therapy. These, along with the appearance of such symptoms as severe diarrhea or constipation, drowsiness, appetite loss, nervousness, persistent mouth ulcers and any other particularly bothersome effects should be immediately brought to the attention of your supervising health care professional.


While taking Nicorandil, avoid taking any of the following medicines: phosphodiesterase 5 inhibitors, vasodilators, tricyclic antidepressants, nitrates, or medicines prescribed to treat hypertension. Also, it is strongly suggested that you avoid drinking alcohol for the duration of your Nicorandil therapy.
Without Prescription (2017)