Neostigmine

 
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Contraindications

Neostigmine is contraindicated if you have any of the following conditions:
- an unusual or allergic reaction to neostigmine, bromides, other medicines, foods, dyes, or preservatives;
- asthma;
- breast-feeding;
- difficulty passing urine;
- heart disease;
- infection in abdomen, peritonitis;
- irregular, slow heartbeat;
- kidney disease;
- pregnant or trying to get pregnant;
- seizures;
- stomach obstruction or ulcers;
- thyroid disease;
- vagotonia;
- if you are allergic to bromides;
- if you are allergic to Neostigmine;
- if you are allergic to other anticholinesterase medications (pyridostigmine);
- if you have a certain abdominal problem (peritonitis);
- if you have a certain nerve disorder (vagotonia);
- if you have any other allergies;
- if you have asthma;
- if you have certain medical conditions;
- if you have heart disease (slow/irregular heartbeat, coronary artery disease);
- if you have overactive thyroid (hyperthyroidism);
- if you have seizures;
- if you have stomach/intestinal blockage;
- if you have stomach/intestinal problems (severe constipation, ulcer, megacolon);
- if you have urinary blockage;

Without a Prescription

Acetylcholine is needed for normal muscle function.
Neostigmine can help with muscle strength.
Neostigmine is prescribed to improve muscle strength in patients with a certain muscle disease (myasthenia gravis).
Neostigmine is prescribed to treat myasthenia gravis.
Neostigmine works by preventing the breakdown of a certain natural substance (acetylcholine) in your body.

Overdose

Reported Neostigmine overdose symptoms are:
- Agitation;
- Blurred vision;
- Diarrhea;
- Dizziness;
- Fast/slow heartbeat;
- Greatly increased saliva/sweating;
- Inability to move;
- Loss of consciousness;
- Muscle cramps/weakness;
- Nausea;
- Trouble breathing;
- Vomiting;

Interactions

Do not take Neostigmine with any of the following drugs:
- antibiotics like kanamycin, neomycin, streptomycin;
- antihistamines for allergy, cough and cold, sleep;
- medicines for heart arrhythmias;
- medicines that cause muscle relaxation;
- other medicines that improve muscle strength or tone;
- some medicines to cause sleep in surgery or to numb pain;
- aminoglycoside antibiotics (gentamicin);
- antiarrhythmic medications (quinidine);
- antihistamines;
- antispasmodics;
- dicyclomine;
- diphenhydramine;
- drugs that decrease the movements of the stomach;
- morphine;
- narcotic pain medications;

Side Effects

Neostigmine side effects that you should report to your health care professional or doctor as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- breathing problems;
- changes in vision;
- chest pain;
- diarrhea;
- difficulty moving;
- feeling dizzy, faint;
- increase in the need to pass urine;
- increased saliva;
- increased sweating;
- irregular, slow heartbeat;
- low blood pressure;
- muscle twitch;
- nausea;
- seizure;
- stomach cramps, gas;
- unusually weak;
- abdominal cramps;
- decreased pupil size;
- diarrhea;
- dizziness;
- headache;
- increased saliva/mucus;
- increased sweating;
- increased urination;
- itching/swelling (especially of the face/tongue/throat);
- nausea;
- new or increased difficulty swallowing;
- new or increased muscle cramps/weakness/twitching;
- rash;
- seizures;
- severe dizziness;
- shortness of breath;
- slow/fast/irregular heartbeat;
- trouble breathing;
- vomiting;
Without Prescription (2017)