Without a Prescription
The other component, benazepril, is an angiotensin-converting enzyme (ACE) inhibitor.
One component, amlodipine, is a calcium channel blocker. It eases the workload of the heart by slowing down the passage of nerve impulses and hence the contractions of the heart muscle.
Lotrel is prescribed when treatment with a single drug has not been successful or has caused side effects.
Lotrel is prescribed in the treatment of high blood pressure.
Lotrel is a combination medicine.
It works by preventing the transformation of a hormone called angiotensin I into a more potent substance that increases salt and water retention in your body.
Lotrel side effects that you should report to your health care professional or doctor as soon as possible:
- Abdominal pain;
- Back pain;
- Bloating and gas;
- Chest pain;
- Decreased sex drive;
- Difficulty swallowing;
- Dry mouth;
- Excessive urination;
- Fluid retention and swelling;
- Hair loss;
- Heart attack;
- Hot flashes;
- Muscle and bone pain;
- Muscle cramps;
- Nerve pain;
- Ringing in the ears;
- Skin disorders;
- Sore throat;
- Swelling of arms and legs;
- Swelling of your face around the lips tongue or throat;
- Upper respiratory infection;
- Weakness and fatigue;
Lotrel is contraindicated if you have any of the following conditions:
- If you are sensitive to or have ever had an allergic reaction to amlodipine, benazepril, or any angiotensin-converting enzyme (ace) inhibitors;
- If you are taking high doses of diuretics;
- If you have congestive heart failure;
- If you have kidney disease or severe liver disease, diabetes, lupus erythematosus, or scleroderma;
- If you have poor kidney function;
- If you notice a yellow coloring to your skin or the whites of your eyes;
Do not take Lotrel with any of the following drugs:
- Diuretics such as diuril, lasix, hydrodiuril;
- Lithium (eskalith, lithobid);
- Potassium supplements (slow-k);
- Potassium-sparing diuretics such as aldactazide, moduretic, and maxzide;
Safety and effectiveness in children have not been established.
Lotrel is available in capsules that contain 2.5 mg of amlodipine and 10 mg of benazepril, capsules containing 5 mg of amlodipine and 10 or 20 mg of benazepril and capsules containing 10 mg of amlodipine and 20 mg of benazepril.
Your doctor will closely monitor the effects of Lotrel and adjust the dosage according to your blood pressure response.
Small, older, frail, or liver-impaired individuals usually start with the lowest dose.
Reported Lotrel overdose symptoms are:
- Rapid heartbeat;
- A sudden drop in blood pressure;