Leuprorelin is contraindicated if you have any of the following conditions:
- an unusual or allergic reaction to Leuprorelin, benzyl alcohol, other medicines, foods, dyes, or preservatives;
- pain or difficulty passing urine;
- pregnant or trying to get pregnant;
- spinal cord metastasis;
- if you are allergic to Leuprorelin;
- if you have any other allergies;
- if you have certain medical conditions;
- if you have depression;
- if you have family history of osteoporosis and broken bones;
- if you have high blood fat levels (high cholesterol, high triglycerides);
- if you have long-term alcohol use;
- if you have smoking;
- if you have to use of certain medications (corticosteroids such as prednisone, certain anti-seizure drugs such as phenytoin);
- if you have vaginal bleeding of unknown cause;
Without a Prescription
For the treatment of fibroids, Leuprorelin is usually given with iron to help improve anemia that is caused by too much vaginal bleeding.
Leuprorelin also shrinks the abnormal uterine tissue that causes these symptoms.
Leuprorelin helps slow down the rate of early bone growth so that the chances for reaching normal adult height are increased.
Leuprorelin helps to delay sexual development (e.g., growth of the breasts/testicles) and the start of menstrual periods.
Leuprorelin helps to reduce symptoms such as pelvic pain, painful/heavy menstrual periods, and abdominal bloating.
Leuprorelin is a man-made hormone.
Leuprorelin is prescribed for other hormonal conditions.
Leuprorelin is prescribed to stop early puberty (precocious puberty) in children.
Leuprorelin is prescribed to treat children with early onset of puberty.
Leuprorelin is prescribed to treat disorders of the uterus (endometriosis, fibroids) in women.
Leuprorelin is prescribed to treat the symptoms of prostate cancer.
Leuprorelin works by decreasing the amount of estrogen that is made in the female body.
Leuprorelin works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).
Uterine tissue needs the female hormone estrogen to grow and spread.
Do not take Leuprorelin with any of the following drugs:
- female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections;
- herbal or dietary supplements, like black cohosh or DHEA;
- male hormones, like testosterone;
Leuprorelin side effects that you should report to your health care professional or doctor as soon as possible:
- Abnormal vaginal bleeding (in girls);
- Aggression in children;
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- Bone pain (in adults);
- Breast changes;
- breast swelling or tenderness;
- breathing problems;
- chest pain;
- decrease in sex drive or performance;
- depression or memory disorders;
- Difficulty concentrating;
- Easily broken bones (in adults);
- Hot flashes (flushing);
- hot flashes;
- Increased sweating;
- Itching/swelling (especially of the face/tongue/throat);
- Joint/muscle aches;
- loss of appetite;
- Memory problems;
- Mental/mood changes;
- Mild burning/pain/bruising at the injection site;
- Mood swings;
- muscle, joint, or bone pains;
- New or worsening depression;
- Night sweats;
- pain at site where injected;
- pain in your legs or groin;
- redness or irritation at site where injected;
- Reduced sexual interest;
- Severe confusion;
- Severe dizziness;
- severe headache;
- Severe vomiting;
- skin problems or acne;
- Sudden severe headache;
- Sudden severe mental/mood changes;
- Swelling of the ankles/feet;
- swelling of the feet and legs;
- Thoughts of suicide;
- Trouble breathing;
- Trouble sleeping;
- Upset stomach;
- Vaginal discomfort/dryness;
- Vision changes;
- visual changes;