Hydroxychloroquine

 
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Without a Prescription

Children are especially sensitive to Hydroxychloroquine.
It is prescribed for lupus erythematosus, a chronic inflammation of the connective tissue.
Keep this drug in a child-proof container and out of the reach of children.
Hydroxychloroquine is prescribed for the prevention and treatment of certain forms of malaria.
Hydroxychloroquine is prescribed to treat the symptoms of rheumatoid arthritis such as swelling, inflammation, stiffness, joint pain.
Relatively small doses of this medication have caused fatalities.

Side Effects

Hydroxychloroquine side effects that you should report to your health care professional or doctor as soon as possible:

Side effects of treatment for an acute malarial attack may include:
- Vomiting;
- Nausea;
- Mild headache;
- Lack or loss of appetite;
- Heart problems;
- Dizziness;
- Diarrhea;
- Abdominal cramps;

Side effects of treatment for lupus erythematosus and rheumatoid arthritis may include:
- Weight loss;
- Weariness;
- Vomiting;
- Vertigo;
- Skin rash;
- Skin inflammation and scaling;
- Skin eruptions;
- Scaly;
- Ringing in the ears;
- Red skin patches);
- Reading difficulties;
- Psoriasis (dry;
- Nightmares;
- Nervousness;
- Nausea;
- Muscle weakness and wasting;
- Muscle paralysis;
- Loss or lack of appetite;
- Loss of hair;
- Liver problems or failure;
- Light intolerance;
- Light flashes and streaks;
- Itching;
- Irritability;
- Involuntary eyeball movement;
- Hives;
- Heart problems;
- Hearing loss;
- Headache;
- halos around lights;
- Eye muscle paralysis;
- Excessive coloring of the skin;
- Emotional changes;
- Dizziness;
- Diminished reflexes;
- Difficulty focusing the eyes;
- Diarrhea;
- Decreased vision;
- Convulsions;
- Blurred vision;
- Blood disorders;
- Blisters in mouth and eyes;
- Blind spots;
- Bleaching of hair;
- Anemia;
- Acne;
- Abnormal eye pigmentation;
- Abdominal cramps;
- "foggy vision;

Contraindications

Hydroxychloroquine is contraindicated if you have any of the following conditions:
- If any severe blood disorder develops that is not attributed to the disease you are being treated for;
- If you are being treated for rheumatoid arthritis and have shown no improvement (such as reduced joint swelling or increased mobility) within 6 months;
- If you are on prolonged therapy with this medication;
- If you are sensitive to or have ever had an allergic reaction to Hydroxychloroquine or similar drugs such as aralen and chloroquine;
- If you are taking a drug that has a tendency to produce dermatitis (inflammation of the skin);
- If you experience ringing in the ears, or other hearing problems;
- If you have any problem with your vision or your eyes;
- If you have psoriasis (a recurrent skin disorder characterized by patches of red, dry, scaly skin) or porphyria (an inherited metabolic disorder affecting the liver or bone marrow);
- If you have suffered partial or complete loss of vision in small areas while taking this medication or similar drugs;

Interactions

Do not take Hydroxychloroquine with any of the following drugs:
- Digoxin (lanoxin);
- Cimetidine (tagamet);
- Aurothioglucose (solganal);
- Any medication that may cause liver damage;

Dosage

ADULTS

Acute Attack of Malaria

The usual starting dose is 800 milligrams, to be followed by 400 milligrams in 6 to 8 hours and 400 milligrams on each of 2 consecutive days.
Alternatively, your doctor may prescribe a single dose of 800 milligrams.

Restraint or Prevention of Malaria

The usual dose is 400 milligrams taken once every 7 days on exactly the same day of each week.
If this is not possible, your doctor will have you take a starting dose of 800 milligrams, which may be divided into 2 doses taken 6 hours apart.
If circumstances permit, preventive therapy should begin 2 weeks prior to exposure.
You should continue this suppressive therapy for 8 weeks after leaving the area where malaria occurs.

Rheumatoid Arthritis

The usual starting dose for adults is 400 to 600 milligrams a day taken with a meal or a glass of milk.
If your condition improves, usually within 4 to 12 weeks, your doctor will reduce the dose to a maintenance level of 200 to 400 milligrams daily.

Lupus Erythematosus

The usual starting dose for adults is 400 milligrams once or twice daily.
You will continue to take this dose for several weeks or months, depending on your response.
For longer-term maintenance therapy, your doctor may reduce the dose to 200 to 400 milligrams per day.

CHILDREN

This drug has not been proved safe for treatment of juvenile arthritis.
For the treatment of malaria, your doctor will calculate the dosage on the basis of your child's weight.

Overdose

Symptoms of an overdose of Hydroxychloroquine may occur within 30 minutes. They include:
- Visual problems;
- Inability to breathe;
- Heart problems and failure;
- Headache;
- Drowsiness;
- Convulsions;
Without Prescription (2017)