Without a Prescription

Fluoxetine is prescribed in treatment of depression and other conditions related to mood and affect, including
- Bulimia nervosa;
- Obsessive-compulsive disorder (OCD);
- Panicdisorder;
- Premenstrual dysphoric disorder;
Certain chemicals in our brain control how we feel. It is thought that low levels of a chemical called serotonin can lead to depression and other conditions.
Fluoxetine is prescribed for the treatment of depression, obsessive compulsive disorder, and bulimia nervosa.
Fluoxetine works by helping to regulate serotonin levels in our body, easing the symptoms of depression, the eating disorder bulimia nervosa, and obsessive-compulsive disorder.


Fluoxetine is contraindicated if you have any of the following conditions:
- If you are being treated with ECT (electroconvulsive therapy);
- If you are pregnant, trying for a baby or breast-feeding;
- If you are taking any other medicines, including those available to buy without a prescription, herbal or complementary medicines;
- If you are under 18 years of age;
- If you have ever had an allergic reaction to this or any other medicine;
- If you have ever suffered from mania (great excitement, hallucinations, difficulty in concentrating or staying still);
- If you have taken a monoamine oxidase inhibitor (MAOI) antidepressant within the last two weeks;
- If you suffer from epilepsy, diabetes mellitus, glaucoma (increased eye pressure), or a bleeding disorder;
- If you suffer from heart, liver or kidney problems;


Do not take Fluoxetine with any of the following drugs:

Increases the effect and toxicity of tricyclics:
- Trimipramine;
- Protriptyline;
- Nortriptyline;
- Imipramine;
- Doxepin;
- Desipramine;
- Clomipramine;
- Amoxapine;
- Amitriptyline;

Increased risk of CNS adverse effects:
- Zolmitriptan;
- Sumatriptan;
- Rizatriptan;
- Naratriptan;
- Frovatriptan;
- Eletriptan;
- Almotriptan;

Increases the effect of phenytoin:
- Ethotoin;
- Fosphenytoin;
- Mephenytoin;
- Phenytoin;

The SSRI increases the effect of anticoagulant:
- Warfarin;
- Dicumarol;
- Anisindione;
- Acenocoumarol;

Risk of serotoninergic syndrome:
- Sibutramine;
- Phenylpropanolamine;
- Phentermine;
- Phendimetrazine;
- Moclobemide;
- Methamphetamine;
- Mazindol;
- Fenfluramine;
- Diethylpropion;
- Dextroamphetamine;
- Dexfenfluramine;
- Benzphetamine;
- Amphetamine;

The SSRI increases the effect of the beta-blocker:
- Propranolol;
- Metoprolol;
- Carvedilol;

Possible serotoninergic syndrome with this combination:
- Troleandomycin;
- Josamycin;
- Erythromycin;
- Cyproheptadine;
- Clarithromycin;

Increased risk of cardiotoxicity and arrhythmias:
- Thioridazine;
- Terfenadine;
- Mesoridazine;
- Astemizole;

Combination associated with possible serotoninergic syndrome:
- Linezolid;
- Dextromethorphan;

Possible ergotism and severe ischemia with this combination:
- Ergotamine;
- Dihydroergotamine;

Increased risk of serotonin syndrome:
- Tramadol;
- Ritonavir;
- Oxycodone;

Possible severe adverse reaction with this combination:
- Tranylcypromine;
- Selegiline;
- Rasagiline;
- Phenelzine;
- Isocarboxazid;

Side Effects

Fluoxetine side effects that you should report to your health care professional or doctor as soon as possible:
- Abdominal pain;
- Anxiety;
- Changes in taste;
- Chills;
- Confusion;
- Constipation;
- Diarrhoea;
- Difficulty breathing;
- Difficulty or frequency urinating (passing water);
- Difficulty sleeping;
- Dizziness (especially when standing or sitting up);
- Dry mouth;
- Feeling or being sick;
- Flushing;
- Hair loss;
- Headache;
- Indigestion;
- Infant persistent pulmonary hypertension;
- Joint or muscle pain;
- Mania, characterized by unusual hyperactivity, elation, or excitability;
- Mood changes;
- Nervousness;
- Other side effects include nausea, difficulty sleeping, anxiety, nervousness, and sleepiness;
- Poor concentration;
- Possible life-threatening serotonin syndrome when used with triptan medicines;
- Rash and possible allergic reactions;
- Reduced appetite;
- Seizures;
- Sexual difficulties;
- Sexual problems, including decreased sexual desire, erectile dysfunction, or difficulty achieving orgasm;
- Shakiness;
- Sleepiness;
- Sore throat;
- Suicidal thoughts or actions, most often noted on dose initiation or increase;
- Sweating;
- Unusual movements;
- Weakness;
- Weight loss;
- Yawning;


Reported Fluoxetine overdose symptoms are:
- Agitation;
- Hypomania;
- Restlessness;

Other Brand Names

In some countries Fluoxetine may also be known as:
- Sarafem;
- Reneuron;
- Pulvules;
- Prozac;
- Prozac Weekly;
- Portal;
- Foxetin;
- Fontex;
- Fluval;
- Fluoxeren;
- Fluctin;
- Eufor;
- Deprex;
- Animex-On;
- Adofen;
Without Prescription (2017)