Diflucan

 
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Without a Prescription

Diflucan capsules, suspension and infusion all contain the active ingredient fluconazole, which is a type of drug called a triazole antifungal. Fluconazole is available without a brand name, ie as the generic drug. Fluconazole is prescribed to treat infections with fungi and yeasts.
Diflucan is prescribed to treat a number of different types of fungal and yeast infections, particularly those caused by Candida or Cryptococcus species of fungi.
Diflucan is prescribed to treat fungal infections called candidiasis (also known as thrush or yeast infections). These include vaginal infections, throat infections, and fungal infections elsewhere in the body, such as infections of the urinary tract, peritonitis (inflammation of the lining of the abdomen), and pneumonia. Diflucan is prescribed to guard against candidiasis in some people receiving bone marrow transplants, and is prescribed to treat meningitis (brain or spinal cord inflammation) caused by another type of fungus.
Diflucan kills the fungi that are causing an infection by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.
In addition, Diflucan is now being prescribed for fungal infections in kidney and liver transplant patients, and fungal infections in patients with AIDS.
It can be taken by mouth or may be administered via a drip into a vein depending on the type and severity of the infection. The length of treatment will depend on the type and severity of the infection, for example vaginal thrush can normally treated with a single dose by mouth, while some other infections may require six to eight weeks of treatment.
The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As fluconazole causes holes to appear in the cell membranes, essential constituents of the fungal cells can leak out. This kills the fungi and treats the infection.

Diflucan is prescribed for the treatment of:
- Candida infections of the linings of the mouth, throat, lungs or urinary tract;
- Fungal infections caused by cryptococcus fungi, including cryptococcal meningitis and infections affecting the lungs or skin;
- Fungal skin infections, such as athlete's foot , ringworm, jock itch, pityriasis versicolor, or candida skin infections;
- Inflammation of the penis and/or foreskin caused by infection with candida albicans;
- Inflammation of the vagina caused by infection with candida albicans;
- Internal fungal infections caused by candida, eg infections of the bloodstream, urinary tract, heart, lungs, abdomen or other widespread internal infections;
- Preventing fungal infections in people with a weakened immune system and low white blood cell counts, for example due to chemotherapy, radiotherapy or bone marrow transplants;
- Preventing relapse of disease caused by cryptococcus fungi, eg cryptococcal meningitis, in people with aids;

Side Effects

Diflucan side effects that you should report to your health care professional or doctor as soon as possible:
- Abdominal pain;
- Allergic reactions;
- Alteration in results of liver function tests;
- Alteration in taste;
- Decrease in the level of potassium in the blood;
- Decrease in the number of white blood cells or platelets in the blood;
- Diarrhoea;
- Dizziness;
- Excess gas in the stomach and intestines;
- Hair loss;
- Headache;
- Indigestion;
- Liver disorders;
- Nausea and vomiting;
- Raised levels of cholesterol in the blood;
- Rash;
- Seizures;
- Severe skin reactions;

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Diflucan.

The most common side effect for people taking more than one dose is nausea.

For women taking a single dose to treat vaginal infection, the most common side effects are abdominal pain, diarrhea, headache, and nausea; changes in taste, dizziness, and indigestion may occur less often.

Other side effects may include:
- Vomiting;
- Skin rash;
- Irregular heartbeat;
- Headache;
- Diarrhea;
- Abdominal pain;

Dosage

CHILDREN

For throat infections

The usual dose for candidiasis of the mouth and throat is 6 mg for each 2.2 pounds of the child's weight on the first day, and 3 mg per 2.2 pounds once a day after that.

The duration of treatment is the same as that for adults.

For systemic (bodywide) infections

Diflucan has been given at 6 to 12 mg per 2.2 pounds of weight per day.

For cryptococcal meningitis

Treatment will last 10 to 12 weeks after the fungus disappears.
The usual dose is 12 mg per 2.2 pounds of body weight per day on the first day, and 6 mg per 2.2 pounds per day after that.

For yeast infections of the esophagus

Cadidiasis in the upper digestive canal is usually treated with a dose of 6 mg per 2.2 pounds of body weight on the first day, and half that amount once daily thereafter.
Daily doses of up to 12 mg per 2.2 pounds of body weight are sometimes prescribed.

ADULTS

For vaginal infections

The usual treatment is a single 150-mg dose.

For throat infections

You should see results in a few days, but treatment should continue for at least 2 weeks to avoid a relapse.
The usual dose for candidiasis of the mouth and throat is 200 mg on the first day, followed by 100 mg once a day.
For candidiasis of the esophagus (gullet) the usual dose is 200 mg on the first day, followed by 100 mg once a day.
Treatment should continue for a minimum of 3 weeks and for at least 2 weeks after symptoms have stopped.
A dose of 400 mg a day can be taken if your infection is more severe.

For urinary infections and peritonitis

Doses range from 50 to 200 mg per day.

For systemic (bodywide) infections

Doses of up to 400 mg per day are sometimes prescribed.

For cryptococcal meningitis

The usual dose is 400 mg on the first day, followed by 200 mg once a day.
Treatment should continue for 10 to 12 weeks once tests of spinal fluid come back negative.
For AIDS patients, a 200-mg dose taken once a day is recommended to prevent relapse.

Prevention of candidiasis during bone marrow transplantation

The usual dose is 400 mg once a day.

If you have kidney disease, your doctor may have to reduce your dosage.
Without Prescription (2017)