Without a Prescription

Busulfan is a popular cancer (antineoplastic) drug that is also widely known under the generic name of Busulfan. A treatment with Busulfan is known to interfere with the multiplication of the malitious cancer cells, slowing their spread in the patient's organism.
Busulfan is regularly prescribed to patients who are suffering from chronic myelogenous leukemia. However, Busulfan could also be prescribed to treat or to prevent some other medical disorders (other types of cancer) that have not been listed in this guide. If you have any questions regarding why you have been prescribed to take Busulfan you should ask your physician for more information.


Busulfan is a powerful drug that must be administered by an authorized healthcare provider or at least under the supervision of a qualified doctor. Patients who have been treated with Busulfan have complained about Busulfan's severe side effects. These side effects include: allergic reactions to Busulfan or to any of it's ingredients (throat closing; breathing difficulties; swelling of the tongue, face or lips; hives); abnormal bruising or bleeding; chills or fever; congestion; persistent cough; breath shortness; stomach, flank or joint pain or discomfort; abnormal fatigue; unusual or sudden weakness; abnormally fast weight loss; decreased appetite; infertility; pronounced vomiting, nausea, dizziness, diarrhea, confusion; secondary cancers; darkening of the skin's natural color; Pulmonary fibrosis (a disease that affects the patient's lungs). Before you start taking Busulfan you should discuss with your personal healthcare provider the risks and the benefits that come along with a treatment with Busulfan.
Before you start using Busulfan you should inform your personal physician if you are suffering from
- Any breathing disorders or lung problems;
- Any type of seizure disease;
- Bone marrow disease;

If you are suffering from any of the medical conditions that have been listed here, you might not be allowed to start taking Busulfan or you might have to be prescribed a lower dose of Busulfan. Your physician might want to closely monitor your treatment with Busulfan.
Busulfan is a category D FDA pregnancy medicine. Therefore, Busulfan can and sometimes does cause unwanted and severe birth defects if it is taken during pregnancy. A prolonged treatment with Busulfan is known to affect a male patient's sperm production and a woman patient's egg production. If you think that you might become pregnant any time soon you must not start a treatment with Busulfan unless your personal physician advises you to. While you are following a treatment with Busulfan you should use an effective birth control method. It has not been clearly determined whether Busulfan's main ingredients can pass into the patient's breast milk or not. If you are breast feeding an infant you should avoid taking Busulfan. Ask your personal healthcare provider for more information.

Intake Guidelines

Ask your personal healthcare provider how and when you should take Busulfan. You should follow all your physician's advices. If you fail to understand some of them you should ask a nurse, a doctor or a pharmacist to explain them to you. If you need further information regarding Busulfan, you should carefully read the set of instructions from the medicine's label. Each dose of Busulfan should be accompanied by a glass of liquid (water).
Busulfan should be taken in on an empty stomach. You must not stop taking Busulfan even if you start to experience vomiting or nausea. Ask your personal physician what to do if vomiting occurs less than 3 hours after you have taken your regular dose of Busulfan.
The injectable form of Busulfan can only be administered by an authorized healthcare provider. While you are being treated with Busulfan you must ensure your organism an adequate hydration. You should drink plenty of liquids. In some cases intravenous administration of fluids is needed.


Your personal physician will properly calculate the correct dose and frequency of intake of Busulfan. The correct dose of Busulfan is known to vary from one case to another, as it depends on a variety of factors such as age, the type of cancer that Busulfan is supposed to treat, general health condition, etc. If you need further information regarding your treatment with Busulfan you should contact your personal physician.


If you suspect that you might be experiencing an overdose with Busulfan you should seek emergency medical attention. Overdose with Busulfan will probably determine a worsening of Busulfan's side effects.

Missed Dose

In order to get the proper benefits from your treatment with Busulfan, you should take it regularly. If you miss one of your doses of Busulfan you should contact your physician and ask him or her for further indications. Do not double dose.

Side Effects

A treatment with Busulfan could trigger some severe side effects such as:
- Allergy;
- Chills or fever;
- Congestion, persistent cough, or breath shortness;
- Unusual bruising or bleeding;
- Weakness or fatigue;

However, Busulfan could also trigger some other less severe and more common side effects such as:
- Dryness of the nose, mouth, and throat;
- Infertility;
- Lack of menstrual period;
- Mouth sores;
- Premature menopause symptoms;
- Rash, itching;
- Temporary hair loss;


While you are being treated with Busulfan you should avoid taking:
- Acetaminophen (tylenol);
- Cyclophosphamide (neosar, cytoxan);
- Itraconazole (sporanox);
- Metronidazole (flagyl);
- Phenytoin (dilantin);

Other Brand Names

In some countries Busulfan may also be known as:
- Busilvex;
- Busulfan;
- Busulfex;
- Misulban;
Without Prescription (2017)