Atovaquone-Proguanil

 
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Contraindications

Atovaquone-Proguanil is contraindicated if you have any of the following conditions:
- Atovaquone;
- Hydroxypropyl cellulose;
- Iron oxide;
- Macrogol;
- Magnesium stearate;
- Methylhydroxypropyl cellulose;
- Microcrystalline cellulose;
- Poloxamer;
- Polyethylene glycol;
- Povidone;
- Proguanil hydrochloride;
- Severe diarrhea;
- Severe kidney problems;
- Sodium starch glycollate;
- The bottle or packaging has shown signs of tampering;
- The expiry date on the bottle has passed;
- The seal around the cap has been broken;
- Titanium dioxide;
- if you are allergic to either atovaquone or proguanil;
- if you have any other allergies;
- if you have current diarrhea;
- if you have current vomiting;
- if you have kidney problems;
- if you have liver problems;
- if you have mental/mood problems;
- if you have seizures;

Without a Prescription

Atovaquone/proguanil belongs to a class of drugs known as antimalarials.
Both medications may be needed for a complete cure and to prevent the return of infection (relapse).
In some cases, you may need to take a different medication (such as primaquine) to complete your treatment.
Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver.
Atovaquone-Proguanil contains 2 medicines: atovaquone and proguanil.
Atovaquone-Proguanil is prescribed for the acute oral treatment of mild to moderate PCP in patients who are intolerant to TMP-SMX.
Atovaquone-Proguanil is prescribed for the treatment or prevention of Pneumocystis carinii pneumonia in patients who are intolerant to trimethoprim-sulfamethoxazole (TMP-SMX).
Atovaquone-Proguanil is prescribed primarily in the prevention and of the treatment of malaria caused by a pathogen known as Plasmodium falciparum.
Atovaquone-Proguanil is prescribed to kill the malaria parasites living inside red blood cells and other tissues.
Atovaquone-Proguanil is prescribed to prevent and treat malaria caused by mosquito bites in countries where malaria is common.

Interactions

Do not take Atovaquone-Proguanil with any of the following drugs:
- zidovudine;
- tetracycline;
- tetracycline;
- rifampin;
- rifabutin;
- rifabutin;
- penicillamine;
- metoclopramide;
- blood thinners (warfarin);
- tetracycline;
- rifampicin;
- rifabutin;
- metoclopramide;
- indinavir;

Other Brand Names

In some countries Atovaquone-Proguanil may also be known as:
- laveran;
- Atovaquone-Proguanil;
- Atovaquone-Proguanil pediatric;
- mepron;
- paludrine;
- proguanil;
- wellvone;

Side Effects

Atovaquone-Proguanil side effects that you should report to your health care professional or doctor as soon as possible:
- cough;
- difficulty in breathing;
- fainting;
- hay fever;
- inability to sleep;
- loss of appetite;
- loss of hair;
- lumpy rash;
- rash or hives;
- stomach pain, nausea, vomiting, diarrhea and mouth ulcers;
- swelling of the lips or mouth;
- tiredness, headache or fever;
- wheezing;
- abdominal pain;
- body aches;
- dark urine;
- diarrhea;
- dizziness;
- fast heartbeat while resting;
- headache;
- high fever;
- itching/swelling (especially of the face/tongue/throat);
- loss of appetite;
- nausea;
- pale skin/lips/nails;
- persistent/severe nausea and vomiting;
- rapid breathing;
- rash;
- severe chills;
- severe dizziness;
- signs of anemia;
- signs of serious liver problems;
- signs of severe infection;
- sore throat;
- trouble breathing;
- unexplained tiredness;
- vomiting;
- weakness;
- worsening tiredness;
- yellowing eyes/skin;
Without Prescription (2017)